Santoro Domenico, Gembillo Guido, Andò Giuseppe
Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Unit of Cardiology, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
J Clin Med. 2020 May 14;9(5):1466. doi: 10.3390/jcm9051466.
The close relationship between kidney and heart is well known. Cardiovascular impairment contributes to the worsening of renal function and kidney failure worsens cardiovascular health. Atrial fibrillation (AF) is a frequent issue in patients with Chronic Kidney Disease (CKD) and several studies have demonstrated that AF impacts negatively on their quality of life and outcomes. Understanding the mechanisms leading to the progression of CKD, new-onset AF and acute myocardial infarction (AMI) is a key issue. The evaluation of Glomerular Filtration Rate (GFR) could make the difference in this equilibrium and suggests specific strategies in the treatment of the population at major risk of cardiovascular events. This intriguing connection paves the way for necessary further investigations.
肾与心之间的密切关系众所周知。心血管损害会导致肾功能恶化，而肾衰竭会使心血管健康恶化。心房颤动（AF）是慢性肾脏病（CKD）患者中常见的问题，多项研究表明AF对他们的生活质量和预后有负面影响。了解导致CKD进展、新发AF和急性心肌梗死（AMI）的机制是一个关键问题。肾小球滤过率（GFR）的评估可能会改变这种平衡，并为治疗心血管事件高危人群提供具体策略。这种有趣的联系为必要的进一步研究铺平了道路。
