Spine Unit, Department of Orthopedic Surgery, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Department of Orthopedics and Scoliosis Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX, USA.
Eur Spine J. 2020 Aug;29(8):2091-2099. doi: 10.1007/s00586-020-06384-w. Epub 2020 May 18.
To investigate the impact of Scheuermann's Kyphosis (SK) on health -related quality of life (HRQOL) in adult patients and compare it to the general population. Moreover, to assess whether location of the kyphosis affects pelvic parameters, HRQOL, and pulmonary function.
Of a cohort of 251 patients seen for a pediatric spinal deformity in the years 1972-1982 in our outpatient clinic, 55 had radiologically verified SK. Thirty-eight participated in the study and responded to HRQOL questionnaires, 34 had radiographs taken and 31 had pulmonary function testing. The patients were divided into two groups according to location of the SK apex: thoracic (Th) above Th10 and thoracolumbar (TL) from Th10 and below. Spinopelvic parameters were measured for all radiographs. The HRQOL scores for all SK patients were compared with normative data from a Scandinavian population. Pulmonary function measurements were compared between the Th and TL SK groups.
Mean follow-up was 39 ± 1.6 years, and mean age at follow-up was 53 ± 2.4 years. We found lower score in the TL group for SRS-22r function domain (p = 0.027) compared with the Th group, but no significant difference in the remaining domains and SRS-22r subscore (p > 0.18). The patients had significantly lower mean scores compared to normative values on SRS-22r domains pain (p = 0.049) and self-image (p = 0.006), but no statistically significant difference on SRS-22r subscore (p = 0.064). There was no difference in pelvic parameters between the two SK groups. We did not find a difference in pulmonary function on percent predicted FEV1 (FEV1%) (p = 0.91) and percent predicted FEV1/FVC (FEV1/FVC%) (p = 0.82) between the two SK groups.
We found a lower HRQOL in adult patients with SK 39 years after diagnosis regarding SRS-22r domains pain and self-image, and a tendency toward lower overall HRQOL compared with a background population. The location of the SK apex did not seem to have an overall impact on HRQOL. There was no difference in pelvic parameters in the two groups and no difference in pulmonary function. These slides can be retrieved under Electronic Supplementary Material.
研究 Scheuermann 后凸(SK)对成年患者健康相关生活质量(HRQOL)的影响,并与普通人群进行比较。此外,评估后凸的位置是否会影响骨盆参数、HRQOL 和肺功能。
在我们的门诊诊所,对 1972 年至 1982 年间因儿科脊柱畸形就诊的 251 名患者进行了队列研究,其中 55 名患者经影像学证实患有 SK。38 名患者参与了这项研究,并回答了 HRQOL 问卷,其中 34 名患者拍摄了 X 光片,31 名患者进行了肺功能测试。根据 SK 顶点的位置,将患者分为两组:胸椎(Th)以上 Th10 和胸腰椎(TL)Th10 以下。对所有 X 光片进行脊柱骨盆参数测量。将所有 SK 患者的 HRQOL 评分与斯堪的纳维亚人群的参考数据进行比较。比较 TL 和 Th SK 组之间的肺功能测量值。
平均随访时间为 39±1.6 年,随访时平均年龄为 53±2.4 岁。与 Th 组相比,TL 组的 SRS-22r 功能域评分较低(p=0.027),但在其余域和 SRS-22r 亚评分上无显著差异(p>0.18)。与参考值相比,患者的 SRS-22r 域疼痛(p=0.049)和自我形象(p=0.006)的平均评分明显较低,但 SRS-22r 亚评分无统计学差异(p=0.064)。两组 SK 患者的骨盆参数无差异。两组间预测的 1 秒用力呼气量百分比(FEV1%)(p=0.91)和预测的 1 秒用力呼气量/用力肺活量百分比(FEV1/FVC%)(p=0.82)的肺功能无差异。
我们发现,诊断后 39 年,SK 成年患者的 HRQOL 较低,SRS-22r 域疼痛和自我形象较差,与背景人群相比,整体 HRQOL 呈下降趋势。SK 顶点的位置似乎对 HRQOL 没有总体影响。两组间骨盆参数无差异,肺功能也无差异。这些幻灯片可在电子补充材料中检索。