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美沙酮辅助阿片类药物戒断及随后的海洛因戒除:心理准备的重要性。

Methadone-Assisted Opiate Withdrawal and Subsequent Heroin Abstinence: The Importance of Psychological Preparedness.

机构信息

Department of Psychology, Faculty of Health, Social Care, and Medicine, Edge Hill University, Ormskirk, UK.

Evidence-Based Practice Research Centre, Faculty of Health, Social Care, and Medicine, Edge Hill University, Ormskirk, UK.

出版信息

Am J Addict. 2021 Jan;30(1):11-20. doi: 10.1111/ajad.13062. Epub 2020 May 19.

Abstract

BACKGROUND AND OBJECTIVES

Treatment guidelines emphasize patients' readiness for transitioning from opiate substitution treatment (OST) to opiate withdrawal and abstinence. Psychological preparedness indicators for this transition were examined.

METHODS

Patients (all male) were recruited from three treatment settings: prison, an inpatient detoxification unit, and an outpatient clinic. Time 1 (T1) was admission to methadone-assisted withdrawal in all settings. Time 2 (T2) was a 6-month follow-up. With n = 24 at T1 for each group (N = 72), a battery of instruments relevant to psychological preparedness was administered.

RESULTS

At T1, inpatients had higher self-efficacy beliefs for successful treatment completion than prison patients. For patients contactable at T2, T1 self-efficacy positively predicted T2 opiate abstinence. No other variable improved prediction. T1 SOCRATES (Stages of Change Readiness and Treatment Eagerness Scale) ambivalence scores, age, and lifetime heroin use duration predicted maintenance of contact or not with treatment services and contactability by the researcher. Measures of mood did not differ between groups at T1 or predict T2 outcomes.

DISCUSSION AND CONCLUSIONS

Self-efficacy beliefs are a potentially useful indicator of readiness for transitioning from OST to a medically assisted opiate withdrawal and subsequent abstinence. Ambivalence regarding change, age, and lifetime heroin use duration are potentially useful predictors of patients maintaining contact with services, and of being retained in research.

SCIENTIFIC SIGNIFICANCE

These findings advance existing literature and knowledge by highlighting the importance of self-efficacy in psychological preparedness for opiate abstinence, and the predictive utility to clinicians of this and other variables measurable at admission, in the clinical management of opiate users. (© 2020 The Authors. The American Journal on Addictions published by Wiley Periodicals LLC on behalf of The American Academy of Addiction Psychiatry). (Am J Addict 2021;30:11-20).

摘要

背景与目的

治疗指南强调患者准备好从阿片类药物替代治疗(OST)过渡到阿片类药物戒断和戒除。本研究检查了这一转变的心理准备指标。

方法

从三种治疗环境中招募了患者(均为男性):监狱、住院戒毒病房和门诊诊所。所有环境中的患者在 T1(时间 1)都接受了美沙酮辅助戒断。T2(时间 2)是 6 个月的随访。T1 时每个组有 n=24 例(N=72),对一组与心理准备相关的工具进行了评估。

结果

T1 时,住院患者对成功完成治疗的自我效能感高于监狱患者。对于可在 T2 联系到的患者,T1 自我效能感正向预测 T2 阿片类药物戒断。没有其他变量能提高预测效果。T1 SOCRATES(改变阶段准备和治疗渴望量表)矛盾得分、年龄和终身海洛因使用时间预测了与治疗服务的维持或中断以及研究人员的可联系性。T1 时各组的情绪测量值没有差异,也不能预测 T2 结果。

讨论与结论

自我效能感是从 OST 过渡到医学辅助阿片类药物戒断和随后戒除的准备状态的一个潜在有用的指标。对改变的矛盾、年龄和终身海洛因使用时间是患者保持与服务联系和被纳入研究的潜在有用预测因素。

科学意义

这些发现通过强调自我效能在阿片类药物戒断心理准备中的重要性,以及在入院时可测量的其他变量对临床医生的预测效用,推进了现有文献和知识。(©2020 作者。美国成瘾杂志由 Wiley 期刊出版公司代表美国成瘾医学科学院出版)。(美国成瘾杂志 2021;30:11-20)。

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