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[阿片类药物脱毒因强烈戒断反应或渴求而提前终止?]

[Is premature termination of opiate detoxification due to intensive withdrawal or craving?].

作者信息

Scherbaum N, Heppekausen K, Rist F

机构信息

Klinik für Psychiatrie und Psychotherapie, Rheinische Kliniken Essen, Universität Duisburg-Essen.

出版信息

Fortschr Neurol Psychiatr. 2004 Jan;72(1):14-20. doi: 10.1055/s-2003-812451.

Abstract

Opiate addicts terminate inpatient detoxification prematurely in about 50% of treatment episodes. Premature termination of treatment is often considered to be motivated by intensive withdrawal symptoms. Therefore, the relation between discontinuing treatment and the intensity of withdrawal symptoms and heroin craving is investigated. 130 opiate addicts consecutively admitted to a detoxification ward daily assessed the intensity of withdrawal symptoms on the Short Opiate Withdrawal Scale (SOWS) as well as the intensity of heroin craving on a visual analogue scale. Withdrawal symptoms were treated by stepwise reduction of methadone and symptom-oriented medication. 66 patients (50.8%) terminated treatment prematurely. However, during the days preceding treatment termination, these patients did not differ from regularly detoxified patients assessed on corresponding days with respect to craving, and reported even less intensity of withdrawal symptoms. In conclusion, neither the intensity of withdrawal symptoms nor the intensity of heroin craving constitutes the primary reason for premature termination of detoxification.

摘要

在大约50%的治疗过程中,阿片类药物成瘾者会过早终止住院戒毒治疗。治疗的过早终止通常被认为是由强烈的戒断症状所驱动。因此,对停止治疗与戒断症状强度及海洛因渴望之间的关系进行了调查。130名连续入住戒毒病房的阿片类药物成瘾者每天使用简短阿片类戒断量表(SOWS)评估戒断症状的强度,并使用视觉模拟量表评估海洛因渴望的强度。通过逐步减少美沙酮剂量和对症用药来治疗戒断症状。66名患者(50.8%)过早终止了治疗。然而,在治疗终止前的几天里,这些患者在渴望方面与在相应日期接受常规戒毒治疗的患者并无差异,并且报告的戒断症状强度甚至更低。总之,戒断症状的强度和海洛因渴望的强度都不是戒毒过早终止的主要原因。

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