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2019新型冠状病毒感染的危重症产科患者成功应用恢复期血浆疗法和瑞德西韦治疗:一例病例报告

The use of convalescent plasma therapy and remdesivir in the successful management of a critically ill obstetric patient with novel coronavirus 2019 infection: A case report.

作者信息

Anderson Jonathon, Schauer Jordan, Bryant Suzanne, Graves Cornelia R

机构信息

University of Tennessee Health Science Center, Nashville, United States.

出版信息

Case Rep Womens Health. 2020 May 16;27:e00221. doi: 10.1016/j.crwh.2020.e00221. eCollection 2020 Jul.

Abstract

Remdesivir is a novel therapeutic with known activity against SARS CoV-2 and related coronaviruses. Remdesivir, as well as convalescent plasma therapy, are currently under investigation as potential therapies for patients with Coronavirus Disease 19 (COVID-19). In this case report we summarize the use of convalescent plasma therapy and then remdesivir as a late addition in the treatment of a critically ill obstetric patient with COVID-19. The patient subsequently improved, was extubated 5 days after initiation of remdesivir, was transitioned to room air 24 h later, and discharged at the completion of remdesivir therapy.

摘要

瑞德西韦是一种对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)及相关冠状病毒具有已知活性的新型治疗药物。瑞德西韦以及恢复期血浆疗法目前正在作为新型冠状病毒肺炎(COVID-19)患者的潜在治疗方法进行研究。在本病例报告中,我们总结了恢复期血浆疗法的使用情况,以及随后将瑞德西韦作为晚期添加药物用于治疗一名患有COVID-19的危重症产科患者的情况。该患者随后病情好转,在开始使用瑞德西韦5天后拔管,24小时后转为呼吸空气,并在瑞德西韦治疗结束时出院。

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本文引用的文献

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COVID-19: Immunology and treatment options.新型冠状病毒肺炎:免疫学与治疗选择。
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