Anderson Jonathon, Schauer Jordan, Bryant Suzanne, Graves Cornelia R
University of Tennessee Health Science Center, Nashville, United States.
Case Rep Womens Health. 2020 May 16;27:e00221. doi: 10.1016/j.crwh.2020.e00221. eCollection 2020 Jul.
Remdesivir is a novel therapeutic with known activity against SARS CoV-2 and related coronaviruses. Remdesivir, as well as convalescent plasma therapy, are currently under investigation as potential therapies for patients with Coronavirus Disease 19 (COVID-19). In this case report we summarize the use of convalescent plasma therapy and then remdesivir as a late addition in the treatment of a critically ill obstetric patient with COVID-19. The patient subsequently improved, was extubated 5 days after initiation of remdesivir, was transitioned to room air 24 h later, and discharged at the completion of remdesivir therapy.
瑞德西韦是一种对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)及相关冠状病毒具有已知活性的新型治疗药物。瑞德西韦以及恢复期血浆疗法目前正在作为新型冠状病毒肺炎(COVID-19)患者的潜在治疗方法进行研究。在本病例报告中,我们总结了恢复期血浆疗法的使用情况,以及随后将瑞德西韦作为晚期添加药物用于治疗一名患有COVID-19的危重症产科患者的情况。该患者随后病情好转,在开始使用瑞德西韦5天后拔管,24小时后转为呼吸空气,并在瑞德西韦治疗结束时出院。