超常期的病因。
Etiology of the supernormal period.
作者信息
Stockbridge N
机构信息
Department of Surgery, University of Alberta, Edmonton, Canada.
出版信息
Biophys J. 1988 Nov;54(5):777-80. doi: 10.1016/S0006-3495(88)83015-7.
Abstract
In many excitable cells, there is a time after the action potential when the threshold for eliciting a second action potential is lower than it is in the steady state. The Hodgkin and Huxley (1952) equations predict such a supernormal period. Using their model, it is shown that the supernormal period results from the slow kinetics of the potassium current and does not depend on sodium current activation or inactivation or on the after-depolarization.
摘要
在许多可兴奋细胞中，动作电位之后存在一段时间，此时引发第二个动作电位的阈值低于稳态时的阈值。霍奇金和赫胥黎（1952年）的方程预测了这样一个超常期。利用他们的模型表明，超常期是由钾电流的缓慢动力学引起的，并不依赖于钠电流的激活或失活，也不依赖于去极化后电位。
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引用本文的文献
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Excitability changes in the crustacean motor axons following activity.活动后甲壳类运动轴突的兴奋性变化。
J Math Biol. 1990;28(5):487-99. doi: 10.1007/BF00164160.
本文引用的文献
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