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大蒜（L.）叶片中环有机硫化合物的结构

Structures of Cyclic Organosulfur Compounds From Garlic ( L.) Leaves.

作者信息

Fukaya Masashi, Nakamura Seikou, Hayashida Hitoshi, Noguchi Daisuke, Nakashima Souichi, Yoneda Taichi, Matsuda Hisashi

机构信息

Department of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto, Japan.

出版信息

Front Chem. 2020 Apr 30;8:282. doi: 10.3389/fchem.2020.00282. eCollection 2020.

DOI:10.3389/fchem.2020.00282
PMID:32426322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7205455/
Abstract

Five new cyclic organosulfur compounds, foliogarlic disulfanes A (), A (), and A () and foliogarlic trisulfane A () and A (), were isolated from the leaves of (garlic). The chemical structures of these compounds were elucidated on the basis of physicochemical evidence including Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). Compounds - were obtained as complex compounds with disulfane or trisulfane and tetrahydro-2-difuro[3,2-:2',3'-]furan-5(5a)-one. In addition, the hypothetical biosynthetic pathways of these compounds were suggested.

摘要

从大蒜叶中分离出五种新的环状有机硫化合物，即叶蒜二硫烷A（）、A（）和A（）以及叶蒜三硫烷A（）和A（）。这些化合物的化学结构是根据包括核磁共振（NMR）和质谱（MS）在内的物理化学证据确定的。化合物 - 是以二硫烷或三硫烷与四氢 - 2 - 二呋喃并[3,2 - :2',3'-]呋喃 - 5(5a)-酮的复合化合物形式获得的。此外，还提出了这些化合物的假设生物合成途径。

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本文引用的文献

1
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J Nat Med. 2019 Mar;73(2):397-403. doi: 10.1007/s11418-018-1272-0. Epub 2018 Dec 8.
2
Rare Sulfur-Containing Compounds, Kujounins A and A and Allium Sulfoxide A, from Allium fistulosum 'Kujou'.来自‘Kujou’大蒜的稀有含硫化合物，库尤宁 A 和 A 以及大蒜亚砜 A。
Org Lett. 2018 Jan 5;20(1):28-31. doi: 10.1021/acs.orglett.7b03234. Epub 2017 Dec 11.
3
Acyclic sulfides, garlicnins L-1-L-4, E, and F, from Allium sativum.来自大蒜的无环硫化物、大蒜素L-1-L-4、E和F。
Natural Products in Cardiovascular Diseases: The Potential of Plants from the Allioideae Subfamily (Ex-Alliaceae Family) and Their Sulphur-Containing Compounds.天然产物在心血管疾病中的应用：葱亚科（原葱科）植物及其含硫化合物的潜力
Plants (Basel). 2022 Jul 25;11(15):1920. doi: 10.3390/plants11151920.
4
Antioxidant Properties and Structure-Antioxidant Activity Relationship of Species Leaves.种属叶片的抗氧化特性及结构-抗氧化活性关系。
Molecules. 2021 Nov 26;26(23):7175. doi: 10.3390/molecules26237175.
5
Characterization of the Volatile Components of Essential Oils of Selected Plants in Kenya.肯尼亚部分植物精油挥发性成分的表征
Biochem Res Int. 2020 Dec 15;2020:8861798. doi: 10.1155/2020/8861798. eCollection 2020.
Chem Pharm Bull (Tokyo). 2014;62(5):477-82. doi: 10.1248/cpb.c14-00003.
4
Cyclic sulfoxides garlicnins B2, B3, B4, C2, and C3 from Allium sativum.来自大蒜的环状亚砜类化合物大蒜宁B2、B3、B4、C2和C3。
Chem Pharm Bull (Tokyo). 2013;61(7):695-9. doi: 10.1248/cpb.c13-00082.
5
Garlicnins B(1), C(1), and D, from the fraction regulating macrophage activation of Allium sativum.大蒜素B(1)、C(1)和D，来自调节巨噬细胞活化的大蒜提取物。
Chem Pharm Bull (Tokyo). 2012;60(6):747-51. doi: 10.1248/cpb.60.747.
6
A scent of therapy: pharmacological implications of natural products containing redox-active sulfur atoms.一种治疗的气息：含氧化还原活性硫原子的天然产物的药理学意义。
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7
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8
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9
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Mol Cancer Ther. 2005 Feb;4(2):325-31.
10
Allyl-thiosulfinates, the bacteriostatic compounds of garlic against Helicobacter pylori.烯丙基硫代亚磺酸盐，大蒜对幽门螺杆菌的抑菌化合物。
Biotechnol Prog. 2004 Jan-Feb;20(1):397-401. doi: 10.1021/bp034143b.