Nohara Toshihiro, Fujiwara Yukio, Ikeda Tsuyoshi, Yamaguchi Koki, Manabe Hideyuki, Murakami Kotaro, Ono Masateru, Nakano Daisuke, Kinjo Junei
Faculty of Pharmaceutical Sciences, Sojo University.
Chem Pharm Bull (Tokyo). 2014;62(5):477-82. doi: 10.1248/cpb.c14-00003.
Six novel acyclic sulfides, named garlicnins L-1-L-4 (1-4), E (5), and F (6), were isolated from the acetone extracts, with the ability to suppress M2 macrophage activation, of the bulbs of garlic (Allium sativum L.), and their chemical structures were characterized.
从大蒜(Allium sativum L.)鳞茎的丙酮提取物中分离出六种新型无环硫化物,命名为蒜素L-1-L-4(1-4)、E(5)和F(6),它们具有抑制M2巨噬细胞活化的能力,并对其化学结构进行了表征。