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一名儿科患者意外接触氯气:病例报告

Accidental Chlorine Gas Exposure in a Pediatric Patient: A Case Report.

作者信息

Antolick Ashley, Ouellette Lindsey, Judge Bryan, Riley Brad, Jones J S

机构信息

Spectrum Health - Michigan State University Emergency Medicine Residency Program, Grand Rapids, Michigan.

出版信息

Clin Pract Cases Emerg Med. 2020 Apr 23;4(2):205-207. doi: 10.5811/cpcem.2020.3.46746. eCollection 2020 May.

DOI:10.5811/cpcem.2020.3.46746
PMID:32426673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7220003/
Abstract

INTRODUCTION

Chlorine gas is a known irritant of the respiratory tract, which may cause damage to various systems depending on time of exposure and concentration of the gas. Current treatments are mainly supportive. While no definitive studies have been completed to date, it has been noted that treatment with a sodium bicarbonate solution via nebulizer may lead to improved outcomes for patients dealing with chlorine gas exposure.

CASE REPORT

We present a case of a nine-year-old child arriving at the emergency department after exposure to chlorine gas. Complete recovery from his symptoms occurred rapidly with the administration of nebulized sodium bicarbonate.

DISCUSSION

Inhaled chlorine gas acts as a mucous membrane irritant, with symptoms usually beginning within minutes of exposure. Inhaled nebulized sodium bicarbonate has been suggested as a therapy for chlorine exposure. Although its mechanism of action is not well understood, it is thought that inhaled sodium bicarbonate neutralizes the hydrochloric acid formed when the chlorine gas reacts with the water in the lungs.

CONCLUSION

Nebulized sodium bicarbonate solution at a low concentration appeared to rapidly and effectively reverse the symptoms due to chlorine gas inhalation in a young child.

摘要

引言

氯气是一种已知的呼吸道刺激物,根据接触时间和气体浓度的不同,可能会对各种系统造成损害。目前的治疗主要是支持性的。虽然迄今为止尚未完成确切的研究,但已经注意到通过雾化器使用碳酸氢钠溶液进行治疗可能会改善氯气接触患者的预后。

病例报告

我们报告一例9岁儿童在接触氯气后抵达急诊科的病例。通过雾化碳酸氢钠治疗,其症状迅速完全恢复。

讨论

吸入的氯气是一种粘膜刺激物,症状通常在接触后几分钟内开始出现。吸入雾化碳酸氢钠已被建议作为氯气接触的一种治疗方法。尽管其作用机制尚不完全清楚,但人们认为吸入的碳酸氢钠会中和氯气与肺内水分反应时形成的盐酸。

结论

低浓度的雾化碳酸氢钠溶液似乎能迅速有效地逆转幼儿因吸入氯气而出现的症状。

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本文引用的文献

1
Emergency management of chlorine gas exposure - a systematic review.氯气中毒的应急管理:系统评价。
Clin Toxicol (Phila). 2019 Feb;57(2):77-98. doi: 10.1080/15563650.2018.1519193. Epub 2019 Jan 23.
2
Pool chemical-associated health events in public and residential settings - United States, 2003-2012, and Minnesota, 2013.美国2003 - 2012年及明尼苏达州2013年公共和住宅环境中与泳池化学品相关的健康事件
MMWR Morb Mortal Wkly Rep. 2014 May 16;63(19):427-30.
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Case files of the University of California San Francisco Medical Toxicology Fellowship: acute chlorine gas inhalation and the utility of nebulized sodium bicarbonate.加利福尼亚大学旧金山分校医学毒理学奖学金病例档案:急性氯气吸入与雾化碳酸氢钠的效用
J Med Toxicol. 2013 Sep;9(3):259-65. doi: 10.1007/s13181-013-0309-8.
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Accidental chlorine gas intoxication: evaluation of 39 patients.意外氯气中毒:39例患者的评估
J Clin Med Res. 2009 Dec;1(5):274-9. doi: 10.4021/jocmr2009.12.1283. Epub 2009 Dec 28.
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The effect of nebulized NaHCO3 treatment on "RADS" due to chlorine gas inhalation.雾化碳酸氢钠治疗对氯气吸入所致“反应性气道功能不全综合征(RADS)”的影响。
Inhal Toxicol. 2006 Oct;18(11):895-900. doi: 10.1080/08958370600822615.
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Nebulized sodium bicarbonate in acute chlorine inhalation.急性氯气吸入时雾化吸入碳酸氢钠
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Treatment of acute chlorine gas inhalation with nebulized sodium bicarbonate.用雾化碳酸氢钠治疗急性氯气吸入
J Emerg Med. 1990 May-Jun;8(3):327-9. doi: 10.1016/0736-4679(90)90014-m.