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用羟基磷灰石/胶原蛋白复合材料修复髂嵴缺损。

Repair of Iliac Crest Defects with a Hydroxyapatite/Collagen Composite.

作者信息

Murata Koichi, Fujibayashi Shunsuke, Otsuki Bungo, Shimizu Takayoshi, Matsuda Shuichi

机构信息

Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

出版信息

Asian Spine J. 2020 Dec;14(6):808-813. doi: 10.31616/asj.2019.0310. Epub 2020 May 21.

Abstract

STUDY DESIGN

Retrospective study.

PURPOSE

This study aimed to assess the effect of refilling with hydroxyapatite/collagen (HAp/Col) composite on an iliac crest defect after spinal fusion.

OVERVIEW OF LITERATURE

The use of iliac crest bone graft has been the gold standard in spinal fusion for a long time because of its biological and non-immunologic properties. Few reports have addressed how bone defects recover after iliac crest bone harvest following spinal fusion.

METHODS

Cancellous bone was collected from the anterior iliac crest during lateral interbody fusion (LIF), and the bone void of the ilium was refilled with a porous HAp/Col composite. We assessed bone recovery using computed tomography (CT). From the 74 patients who underwent LIF between January 2015 and December 2016, we included 49 patients whose iliac crest could be evaluated using CT at 3 months and 1 year after the surgery.

RESULTS

Bone defects decreased in a time-dependent manner after the surgery. Cortical closure was observed in 28.5% of the cases 3 months after the surgery; at 1 year postoperatively, 95.9% of the patients had cortical closure. Complete repair of the cancellous bone was achieved in 57.1% of the patients at 3 months after the surgery and in 95.9% at 1 year after the surgery. There were no significant hematomas, infections, iliac crest fractures, or soft tissue herniation.

CONCLUSIONS

Radiographic recovery of cortical and cancellous bone defects was achieved with high probability via refilling with HAp/Col composite over the 1-year period.

摘要

研究设计

回顾性研究。

目的

本研究旨在评估用羟基磷灰石/胶原蛋白(HAp/Col)复合材料填充对脊柱融合术后髂嵴缺损的影响。

文献综述

由于其生物学和非免疫特性,长期以来髂嵴骨移植一直是脊柱融合的金标准。很少有报道探讨脊柱融合术后髂嵴取骨后骨缺损如何恢复。

方法

在外侧椎间融合术(LIF)期间从髂前嵴采集松质骨,并用多孔HAp/Col复合材料填充髂骨的骨缺损。我们使用计算机断层扫描(CT)评估骨恢复情况。在2015年1月至2016年12月期间接受LIF的74例患者中,我们纳入了49例在术后3个月和1年可以用CT评估髂嵴的患者。

结果

术后骨缺损呈时间依赖性减少。术后3个月,28.5%的病例观察到皮质闭合;术后1年,95.9%的患者出现皮质闭合。术后3个月,57.1%的患者实现了松质骨的完全修复,术后1年为95.9%。没有明显的血肿、感染、髂嵴骨折或软组织疝。

结论

通过用HAp/Col复合材料填充,在1年期间皮质和松质骨缺损有很高概率实现影像学恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac0/7788373/d14608e3bef5/asj-2019-0310f1.jpg

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