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用于临床和研究应用的超声成像的心脏组织模拟弹道凝胶体模。

Cardiac Tissue-Mimicking Ballistic Gel Phantom for Ultrasound Imaging in Clinical and Research Applications.

机构信息

Sunnybrook Research Institute, Toronto, Ontario, Canada.

Conavi Medical, North York, Ontario, Canada.

出版信息

Ultrasound Med Biol. 2020 Aug;46(8):2057-2069. doi: 10.1016/j.ultrasmedbio.2020.03.011. Epub 2020 May 16.

Abstract

Ballistic gel was investigated as a tissue-mimicking material in an anthropomorphic cardiac phantom for ultrasound imaging. The gel was tested for its acoustic properties and its compatibility with conventional plastics molding techniques. Speed of sound and attenuation were evaluated in the range 2-12 MHz. The speed of sound was 1537 ± 39 m/s, close to typical values for cardiac tissue (∼1576 m/s). The attenuation coefficient was 1.07 dB/cm·MHz, within the range of values previously reported for cardiac tissue (0.81-1.81 dB/cm·MHz). A cardiac model based on human anatomy was developed using established image segmentation processes and conventional plastic molding techniques. Key anatomic features were observed, captured and identified in the model using an intracardiac ultrasound imaging system. These favorable results along with the material's durability and processes that allow for repetitive production of detailed whole-heart models at low cost are promising. There are numerous applications for geometrically complex phantoms in research, training, device development and clinical use.

摘要

水凝胶被研究作为一种组织模拟材料,用于超声成像的拟人化心脏体模。该凝胶的声学特性及其与传统塑料成型技术的兼容性进行了测试。声速和衰减在 2-12MHz 的范围内进行了评估。声速为 1537±39m/s,接近心脏组织的典型值(约 1576m/s)。衰减系数为 1.07dB/cm·MHz,在先前报道的心脏组织的范围内(0.81-1.81dB/cm·MHz)。使用已建立的图像分割过程和传统的塑料成型技术,开发了一种基于人体解剖结构的心脏模型。使用心内超声成像系统观察、捕获和识别模型中的关键解剖特征。这些良好的结果,以及该材料的耐用性和允许以低成本重复生产详细的整个心脏模型的工艺,具有广阔的应用前景。在研究、培训、设备开发和临床应用中,几何复杂的体模有许多应用。

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