Wellcome Centre for Integrative Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow G12 8QQ, UK.
Institute of Immunology and Infection Research, University of Edinburgh, Ashworth Laboratories, King's Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Trends Parasitol. 2020 Jul;36(7):582-591. doi: 10.1016/j.pt.2020.04.012. Epub 2020 May 16.
Despite accelerating progress towards schistosomiasis control in sub-Saharan Africa, several age groups have been eclipsed by current treatment and monitoring strategies that mainly focus on school-aged children. As schistosomiasis poses a threat to people of all ages, unfortunate gaps exist in current treatment coverage and associated monitoring efforts, preventing subsequent health benefits to preschool-aged children as well as certain adolescents and adults. Expanding access to younger ages through the forthcoming pediatric praziquantel formulation and improving treatment coverage in older ages is essential. This should occur alongside formal inclusion of these groups in large-scale monitoring and evaluation activities. Current omission of these age groups from treatment and monitoring exacerbates health inequities and has long-term consequences for sustainable schistosomiasis control.
尽管撒哈拉以南非洲地区在控制血吸虫病方面取得了加速进展,但目前的治疗和监测策略主要集中在学龄儿童,这使得几个年龄组被忽视。由于血吸虫病对所有年龄段的人都构成威胁,因此目前的治疗覆盖率和相关监测工作存在一些不足之处,这使得学龄前儿童以及某些青少年和成年人无法获得后续的健康益处。扩大针对年幼年龄组的治疗机会,并提高年长年龄组的治疗覆盖率,这一点至关重要。这应该与这些群体正式纳入大规模监测和评估活动同时进行。目前,这些年龄组在治疗和监测方面被忽视,加剧了健康不平等,对可持续的血吸虫病控制也有长期影响。