Jacob Solomon M, Akinbo Sophie Y, Oluwole Akinola S, Agbana Temitope, Omoruyi Zainab, Okungbowa Michael A, Diehl Jan-Carel, Akinbo Fredrick O
Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria.
Department of Public Health, Federal Ministry of Health, P.M.B. 083, Garki, Abuja 900108, Nigeria.
Int J Environ Res Public Health. 2025 Apr 24;22(5):672. doi: 10.3390/ijerph22050672.
One of the global strategies for the elimination of schistosomiasis is by Mass Drug Administration (MDA) of a single oral dose of praziquantel (40 mg/kg) without a prior individual diagnosis, with a target of >75% treatment coverage among school-aged children. This study was conducted to determine the endemicity of schistosomiasis among school-aged children and adults in Abuja, Nigeria. A total of 1370 participants were recruited, which consisted of 667 (48.67%) males and 703 (51.31%) females. Urine and stool specimens were collected from each participant and analyzed using standard procedures. The overall prevalence of schistosomiasis was 27.5% in this study with Abuja Municipal having the highest prevalence of 49%, while the least (6.1%) was reported in Bwari LAC. The prevalence of schistosomiasis significantly differs ( < 0.05) between the area councils. The location of communities significantly affected the prevalence of schistosomiasis in Abaji, AMAC, and Gwagwalada LACs ( < 0.005). The recovered in this study were and . The prevalence of schistosomiasis increased from the baseline of 21.1% to 49% in Gwagwalada LAC. Gender significantly affected the prevalence of schistosomiasis as more males were infected (33.1%) than their female counterparts (22.2%) ( < 0.05). The prevalence of schistosomiasis was 31% and 23.9% among SAC and adults, respectively. The participants' activities in the river significantly affected the prevalence of schistosomiasis in this study ( < 0.05). The clamour for urgent government and non-government intervention through alternate sources of water like boreholes or pipe-borne water, as well as implementing a behavioural change campaign across the communities to prevent the recurrence, are advocated.
消除血吸虫病的全球战略之一是在不进行个体诊断的情况下，对学龄儿童群体实施单剂量口服吡喹酮（40毫克/千克）的群体药物治疗（MDA），目标是使学龄儿童的治疗覆盖率超过75%。本研究旨在确定尼日利亚阿布贾学龄儿童和成人中血吸虫病的流行情况。共招募了1370名参与者，其中男性667名（48.67%），女性703名（51.31%）。从每位参与者收集尿液和粪便样本，并使用标准程序进行分析。本研究中血吸虫病的总体患病率为27.5%，其中阿布贾市患病率最高，为49%，而布瓦里行政区患病率最低（6.1%）。各地区议会之间血吸虫病的患病率存在显著差异（<0.05）。社区位置对阿巴吉、阿布贾市政区和瓜瓜瓦拉达行政区的血吸虫病患病率有显著影响（<0.005）。本研究中回收的是 和 。瓜瓜瓦拉达行政区的血吸虫病患病率从基线的21.1%上升到了49%。性别对血吸虫病患病率有显著影响，男性感染率（33.1%）高于女性（22.2%）（<0.05）。学龄儿童和成人中血吸虫病的患病率分别为31%和23.9%。参与者在河流中的活动对本研究中血吸虫病的患病率有显著影响（<0.05）。提倡政府和非政府通过钻孔取水或管道供水等替代水源进行紧急干预，并在各社区开展行为改变运动以防止疾病复发。
