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Takayasu 动脉炎的冠状动脉受累:报告的系统回顾。

Coronary artery involvements in Takayasu arteritis: systematic review of reports.

机构信息

Department of Cardiothoracic Surgery, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, Fujian, People's Republic of China.

Department of Clinical Laboratory, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, 389 Longdejing Street, Chengxiang District, Putian, 351100, Fujian, People's Republic of China.

出版信息

Gen Thorac Cardiovasc Surg. 2020 Sep;68(9):883-904. doi: 10.1007/s11748-020-01378-3. Epub 2020 May 19.

DOI:10.1007/s11748-020-01378-3
PMID:32430746
Abstract

Coronary artery involvements in patients with Takayasu arteritis (TA) have not been sufficiently described. By comprehensive retrieval of the pertinent literature published in the past two decades, 59 reports including 141 patients were recruited into this study. In TA patients with coronary artery involvements, the right coronary artery was the most commonly affected. Stenosis was the most common coronary artery lesion, and the coronary ostium was the most commonly affected coronary segment. Acute myocardial infarction was diagnosed in 17 (12.1%) patients of this cohort. Patients receiving surgical treatment showed a higher recovery rate than interventionally treated patients. Interventional therapy was associated with a higher reintervention rate than surgical treatment. The inflammation condition in TA patients can lead to in-stent restenosis and warrant reinterventions. Surgical treatment is a preferable treatment of choice over interventional therapy for the coronary artery lesions of TA patients.

摘要

冠状动脉受累在 Takayasu 动脉炎(TA)患者中尚未得到充分描述。通过对过去二十年发表的相关文献进行全面检索,共纳入了 59 篇报告,包括 141 名患者。在有冠状动脉受累的 TA 患者中,右冠状动脉最常受累。狭窄是最常见的冠状动脉病变,冠状动脉开口是最常受累的冠状动脉节段。该队列中有 17 名(12.1%)患者被诊断为急性心肌梗死。接受手术治疗的患者比接受介入治疗的患者恢复率更高。介入治疗与手术治疗相比,再介入率更高。TA 患者的炎症状况可导致支架内再狭窄,需要再次介入治疗。对于 TA 患者的冠状动脉病变,手术治疗是比介入治疗更好的治疗选择。

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CD8 cell-derived granzyme B may be a predictor for coronary artery involvement and MACE in Takayasu arteritis patients.
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