用乙醇对大鼠进行长期处理会降低分离出的肝细胞核中的RNA聚合酶活性。
Chronic ethanol treatment of rats reduces RNA polymerase activity in isolated liver nuclei.
作者信息
Boyadjiev S, Boyadjieva N, Pironcheva G, Karagyozov L
机构信息
Medico-Biological Institute, Medical Academy, Sofia, Bulgaria.
出版信息
Cytobios. 1988;56(226-227):195-8.
PMID:3243090
Abstract
The effect of acute and chronic ethanol treatment of rats on the activity of RNA polymerases I and II in isolated nuclei has been studied. Results indicate that acute ethanol administration does not change the activity of the nuclear RNA polymerases while chronic ethanol treatment significantly reduces the activity of both RNA polymerases I and II.
摘要
研究了急性和慢性乙醇处理大鼠对分离细胞核中RNA聚合酶I和II活性的影响。结果表明，急性给予乙醇不会改变核RNA聚合酶的活性，而慢性乙醇处理则会显著降低RNA聚合酶I和II的活性。
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