Af Edholm Arvidsson Karolina, Paucar Martin, Svenningsson Per
ST-läkare, neurologi, Danderyds sjukhus.
specialistläkare, Tema neuro, Karolinska universitetssjukhuset.
Lakartidningen. 2020 May 20;117:FX4L.
Orthostatic tremor is a rare and often neglected diagnosis with a synchronised bilateral high frequency tremor of 13-18 Hz, affecting primarily the legs and trunk muscles while standing. The patient is troubled by an intense feeling of unsteadiness. Tremor and unsteadiness diminish significantly by sitting down or starting to walk. The exact pathophysiology is yet unknown but is considered to involve a disruption in the cerebello-thalamo-cortical network supporting balance and adjustements of standing position. The feeling of unsteadiness is probably increased by a proprioceptive disturbance caused by the high frequency tremor.
直立性震颤是一种罕见且常被忽视的病症，表现为双侧同步的13 - 18赫兹高频震颤，主要影响站立时的腿部和躯干肌肉。患者会因强烈的不稳定感而困扰。坐下或开始行走时，震颤和不稳定感会显著减轻。确切的病理生理学尚不清楚，但被认为涉及支持平衡和站立姿势调整的小脑 - 丘脑 - 皮质网络的紊乱。高频震颤引起的本体感觉障碍可能会加重不稳定感。
