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阈下二极管微脉冲激光（SDM）治疗视网膜前膜剥脱术后持续性黄斑增厚及视力受限

Subthreshold Diode Micropulse Laser (SDM) for Persistent Macular Thickening and Limited Visual Acuity After Epiretinal Membrane Peeling.

作者信息

Luttrull Jeffrey K

机构信息

Private Practice, Ventura County Retina Vitreous Medical Group, Ventura, CA 93003, USA.

出版信息

Clin Ophthalmol. 2020 Apr 29;14:1177-1188. doi: 10.2147/OPTH.S251429. eCollection 2020.

DOI:10.2147/OPTH.S251429
PMID:32431487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7198445/
Abstract

PURPOSE

To examine the effect of low-intensity/high-density subthreshold diode micropulse laser (SDM) on visual acuity (VA) and macular thickness in eyes with limited visual recovery and persistent macular thickening after epiretinal membrane peeling.

METHODS

A retrospective review of medical records identified all patients undergoing SDM after membrane peeling in a clinical vitreoretinal subspecialty practice. Exclusion criteria included other obfuscating ocular disease or loss to follow-up after SDM treatment.

RESULTS

All 19 eyes of 18 patients identified were included for study. After membrane peeling, VA improved from an avg. Snellen 20/240 [logMAR 1.08] to 20/72 [0.56] (p=0.0004). Attributed to persistent macular thickening following membrane peeling, overall VAs then gradually declined to an avg. of 20/91 [0.66] by 4-109 months (avg. 41) post vitrectomy, at which point panmacular SDM was performed. An avg. 15 months post SDM, both VA (to avg. 20/68 [0.53]) and maximum macular thickness improved (p=0.007 and p=0.008, respectively). There were no adverse treatment effects.

CONCLUSION

Low-intensity/high-density subthreshold (sublethal) diode micropulse laser (SDM) may reduce macular thickening and improve visual in eyes with persistent macular thickening after membrane peeling even years after vitrectomy.

摘要

目的

探讨低强度/高密度阈下二极管微脉冲激光（SDM）对视网膜前膜剥除术后视力恢复有限且黄斑持续增厚的眼睛的视力（VA）和黄斑厚度的影响。

方法

对临床玻璃体视网膜亚专业实践中所有接受视网膜前膜剥除术后SDM治疗的患者的病历进行回顾性研究。排除标准包括其他混淆性眼病或SDM治疗后失访。

结果

确定的18例患者的19只眼睛均纳入研究。视网膜前膜剥除术后，视力从平均Snellen 20/240[logMAR 1.08]提高到20/72[0.56]（p = 0.0004）。由于视网膜前膜剥除术后黄斑持续增厚，整体视力随后逐渐下降，在玻璃体切除术后4 - 109个月（平均41个月）时平均降至20/91[0.66]，此时进行了全黄斑SDM治疗。SDM治疗后平均15个月，视力（提高到平均20/68[0.53]）和最大黄斑厚度均有所改善（分别为p = 0.007和p = 0.008）。未观察到不良治疗效果。

结论

低强度/高密度阈下（亚致死）二极管微脉冲激光（SDM）可能会减轻视网膜前膜剥除术后黄斑持续增厚患者的黄斑增厚程度，并改善其视力，即使在玻璃体切除术后数年也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/6fbbc5072eef/OPTH-14-1177-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/b96b0ba4a535/OPTH-14-1177-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/7987be7d5417/OPTH-14-1177-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/c211e1e37878/OPTH-14-1177-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/8780cb61fe85/OPTH-14-1177-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/3f88393eedb3/OPTH-14-1177-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/19d93aa86185/OPTH-14-1177-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/5e8c06ceec59/OPTH-14-1177-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/44c4757f5706/OPTH-14-1177-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/8616359d36e8/OPTH-14-1177-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/6fbbc5072eef/OPTH-14-1177-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/b96b0ba4a535/OPTH-14-1177-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/7987be7d5417/OPTH-14-1177-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/c211e1e37878/OPTH-14-1177-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/8780cb61fe85/OPTH-14-1177-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/3f88393eedb3/OPTH-14-1177-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/19d93aa86185/OPTH-14-1177-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/5e8c06ceec59/OPTH-14-1177-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/44c4757f5706/OPTH-14-1177-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/8616359d36e8/OPTH-14-1177-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11c/7198445/6fbbc5072eef/OPTH-14-1177-g0010.jpg

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