Burdelia L G
Eksp Onkol. 1988;10(6):42-4.
The effect of casein-induced peritoneal neutrophils (Nph) of Syrian hamsters on the proliferative activity of normal, embryonal, transformed, and tumour cells was determined by their ability to inhibit or to stimulate 3H-thymidine incorporation in the replicating target cells. The enhanced proliferation of normal embryonal cells (HE) of hamsters was observed after their in vitro contact with Nph, in contrast to the cells of SFHE (spontaneously transformed in vitro HE cells of low tumourigenicity) which were highly susceptible to cytostatic activity of Nph. The high-tumourigenic cells of Syrian hamster tumour strains in vivo or in vitro transformed by Rous sarcoma virus (RSV) were highly resistant to cytostatic activity of Nph.
通过叙利亚仓鼠酪蛋白诱导的腹腔中性粒细胞（Nph）抑制或刺激复制靶细胞中3H-胸腺嘧啶核苷掺入的能力，来确定其对正常、胚胎、转化和肿瘤细胞增殖活性的影响。与低致瘤性的体外自发转化的HE细胞（SFHE细胞）相比，仓鼠正常胚胎细胞（HE）在体外与Nph接触后观察到增殖增强，而SFHE细胞对Nph的细胞抑制活性高度敏感。体内或体外经劳氏肉瘤病毒（RSV）转化的叙利亚仓鼠肿瘤株的高致瘤性细胞对Nph的细胞抑制活性高度抗性。
