Lavnikova N A, Gorbatova E A
Eksp Onkol. 1989;11(1):57-9.
High antitumour activity of Syrian hamster peritoneal cells (PC) is demonstrated in the cytostatic test in vitro. The cytostatic effect (CSE) of PC on hamster cell strains can be revealed at the very early stage (7 hours of cocultivation) and it remains stable during at least 24 hours. Single intraperitoneal injection of physiological (10(-9) M) or pharmacological (10(-7)) doses of prostaglandin E2 preparation leads to the prolonged and significant inhibition of CSE of PC.
叙利亚仓鼠腹腔细胞(PC)在体外细胞生长抑制试验中显示出高抗肿瘤活性。PC对仓鼠细胞株的细胞生长抑制作用(CSE)在共培养的早期阶段(7小时)即可显现,并且在至少24小时内保持稳定。单次腹腔注射生理剂量(10^(-9) M)或药理剂量(10^(-7))的前列腺素E2制剂会导致PC的CSE受到长期且显著的抑制。