Lu Xuefang, Gong Wei, Peng Zhoufeng, Zeng Feifei, Liu Fang
Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China.
Front Med (Lausanne). 2020 May 4;7:168. doi: 10.3389/fmed.2020.00168. eCollection 2020.
To explore the clinical characteristics and dynamic follow-up changes of high resolution CT (HRCT) in 270 patients with Coronavirus Disease 2019 (COVID-19) pneumonia. Two hundred seventy COVID-19 pneumonia patients were retrospectively analyzed, including 146 males and 124 females, with median age of 51 (9,89). The clinical features, laboratory examination indexes and HRCT evolution findings of 270 COVID-19 pneumonia patients were analyzed. 264 cases (95.74%) were positive at the first time nucleic acid test, 6 cases (2.22%) were negative, after multiple inspections, 270 cases (100%) were positive. According to the number of lung segments involved in the lesion, the lesions range from <30% of the lung area (Common type), 30-50% (Severe type), and> 50% (Critical type). At the first CT exam, 136 cases (50.37%) of the common type, 89 cases (32.96%) of the severe type and 45 cases (16.67%) of the critical type. At the second CT exam, 84 cases (31.11%) of the common type, 103 cases (38.15%) of the severe type and 83 cases (30.74%) of the critical type. In the third CT exam, there were 151 cases (55.93%) of the common type, 86 cases (31.85%) of the severe type and 33 cases (12.22%) of the critical type. The differences in image typing were statistically significant ( < 0.05). During this study, a total of 173 patients (64.08%) were recovered after treatment. In some epidemiological backgrounds, CT imaging manifestations and evolutionary characteristics are of great significance for early warning of lung injury, assessment of disease severity, and assistance in clinical typing and post-treatment follow-up.
探讨270例新型冠状病毒肺炎(COVID-19)患者的高分辨率CT(HRCT)临床特征及动态随访变化。回顾性分析270例COVID-19肺炎患者,其中男性146例,女性124例,年龄中位数为51(9,89)。分析270例COVID-19肺炎患者的临床特征、实验室检查指标及HRCT演变结果。264例(95.74%)首次核酸检测呈阳性,6例(2.22%)呈阴性,经多次检测后,270例(100%)均呈阳性。根据病变累及肺段数量,病变范围从<30%肺面积(普通型)、30-50%(重型)和>50%(危重型)。首次CT检查时,普通型136例(50.37%),重型89例(32.96%),危重型45例(16.67%)。第二次CT检查时,普通型84例(31.11%),重型103例(38.15%),危重型83例(30.74%)。第三次CT检查时,普通型151例(55.93%),重型86例(31.85%),危重型33例(12.22%)。图像分型差异有统计学意义(<0.05)。本研究期间,共有173例患者(64.08%)治疗后康复。在某些流行病学背景下,CT影像表现及演变特征对肺损伤预警、疾病严重程度评估、临床分型及治疗后随访具有重要意义。