Franco R, Barlattani A, Perrone M A, Basili M, Miranda M, Costacurta M, Gualtieri P, Pujia A, Merra G, Bollero P
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2020 May;24(9):5036-5045. doi: 10.26355/eurrev_202005_21196.
Obesity is linked to other systemic diseases, such as diabetes mellitus, dyslipidemia, and arterial hypertension. These comorbidities increase the risk of developing cardiovascular disease risk. Adipose tissue is a true endocrine organ and releases various pro-inflammatory cytokines. Periodontal disease (PD) is a chronic inflammatory disorder of the gingiva and bone support (periodontal tissues) that surrounds the teeth. The relationship between obesity and an increased risk of developing PD is already known in the literature. Many studies correlated the cardiometabolic risk with periodontal disease. Bariatric surgery is a way to reduce the adipose tissue in obese patients, that meet specific criteria. It has been observed that this type of surgery usually reduces both the systemic inflammation and the cardiometabolic risk. Some authors have hypothesized that, as a result, the progression of periodontal disease is also reduced. Five articles are analyzed in this systematic review. In these papers, the periodontal health before and after the bariatric surgery was compared. However, the conclusion of the previous studies demonstrated a scarce literature and did not confirm the reduction of periodontal disease after bariatric surgery, but a reduction of cardiometabolic risk. Therefore, periodontal disease in no way influences the reduction of cardiovascular risk after bariatric surgery.
肥胖与其他全身性疾病有关,如糖尿病、血脂异常和动脉高血压。这些合并症会增加患心血管疾病的风险。脂肪组织是一个真正的内分泌器官,会释放各种促炎细胞因子。牙周病(PD)是牙龈和围绕牙齿的骨支持组织(牙周组织)的慢性炎症性疾病。肥胖与患牙周病风险增加之间的关系在文献中已有记载。许多研究将心脏代谢风险与牙周病联系起来。减肥手术是一种减少符合特定标准的肥胖患者体内脂肪组织的方法。据观察,这种手术通常会降低全身炎症和心脏代谢风险。一些作者推测,其结果是牙周病的进展也会减缓。本系统评价分析了五篇文章。在这些论文中,比较了减肥手术前后的牙周健康状况。然而,先前研究的结论显示相关文献较少,并未证实减肥手术后牙周病有所减轻,只是心脏代谢风险有所降低。因此,牙周病对减肥手术后心血管风险的降低没有任何影响。