Fioretti P, Baardman T, Deckers J, Salm E, Zwiers G, Kazemier M, Roelandt J
Thoraxcenter, Erasmus University Rotterdam, The Netherlands.
Eur Heart J. 1988 Nov;9 Suppl L:89-94. doi: 10.1093/eurheartj/9.suppl_l.89.
The aim of this study was to assess the social fate (work resumption) and long-term (four years) survival in 141 patients who completed a cardiac rehabilitation programme after a recent myocardial infarction. Out of the 100 patients who had been working up to recently before the myocardial infarction, 58 resumed their work. Of the predischarge evaluation (clinical data, resting radionuclide ventriculography, bicycle ergometry and 24-h ambulatory ECG monitoring) and bicycle ergometry after the rehabilitation, the only significant predictor of work resumption was a better exercise tolerance at discharge (P less than 0.02). Work was resumed by 68% of white-collar workers and by 52% of blue-collar workers. The four-year cardiac mortality in patients who completed the rehabilitation was 8.5% (N = 12). Four patients died during the first year. Clinical, ventriculographic and ergometric variables collected at hospital discharge, which were related to left ventricular dysfunction, were predictive of survival, while ventricular arrhythmias and markers of myocardial ischaemia were less predictive. The exercise testing performed after the rehabilitation programme was not useful for risk assessment. It is concluded that markers of left-ventricular dysfunction are predictive of a poor outcome; however, due to the low risk of patients who were referred to our rehabilitation unit and completed the rehabilitation programme, it seems reasonable for return to work to be based primarily on clinical information, exercise tolerance, and on psychological and social grounds. An additional extensive cardiological evaluation should be individually tailored for patients with specific symptoms.
本研究旨在评估141例近期心肌梗死后完成心脏康复计划的患者的社会结局(恢复工作情况)和长期(四年)生存率。在心肌梗死前一直工作的100例患者中,58例恢复了工作。在出院前评估(临床数据、静息放射性核素心室造影、运动平板试验和24小时动态心电图监测)以及康复后的运动平板试验中,恢复工作的唯一显著预测因素是出院时更好的运动耐量(P<0.02)。68%的白领工人和52%的蓝领工人恢复了工作。完成康复的患者四年心脏死亡率为8.5%(N = 12)。4例患者在第一年死亡。出院时收集的与左心室功能障碍相关的临床、心室造影和运动变量可预测生存率,而室性心律失常和心肌缺血标志物的预测性较差。康复计划后进行的运动试验对风险评估无用。结论是左心室功能障碍标志物可预测不良结局;然而,由于转诊至我们康复科并完成康复计划的患者风险较低,基于临床信息、运动耐量以及心理和社会因素恢复工作似乎是合理的。对于有特定症状的患者,应根据个体情况进行额外的全面心脏评估。