Fioretti P, Simoons M L, Zwiers G, Baardman T, Brower R W, Kazemir M, Hugenholtz P G
Thoraxcenter, Erasmus University Rotterdam, The Netherlands.
Eur Heart J. 1987 Oct;8 Suppl G:33-8. doi: 10.1093/eurheartj/8.suppl_g.33.
The aim of this study was to assess whether data related to predischarge clinical examinations, resting radionuclide ventriculography and symptom-limited bicycle ergometry can predict the achievement of a normal exercise capacity after a rehabilitation program in patients with a recent myocardial infarction. The study population consists of 141 consecutive patients who completed a 3-month training program. Patients with heart failure and/or severe angina were excluded. The rehabilitation program included two training sessions weekly during the 3 months. Working capacity (WC) increased from 79 +/- 17% at hospital discharge to 105 +/- 21% of normal values after rehabilitation (P less than 0.001), by 33% on average. Ninety-five patients achieved a normal WC. Conventional predischarge clinical evaluation, resting left ventricular ejection fraction, exercise induced angina, or ST segment depression were not predictive of normal WC after rehabilitation. Predischarge WC was the single best predictor of a normal WC after rehabilitation compared to those with a persistently low WC (84 +/- 15% in patients with normal WC vs 69 +/- 14% in those with persistently low WC, P less than 0.001). Nevertheless, 49% of patients with a baseline WC of less than 80% achieved a normal WC after rehabilitation. No correlation was found between the change of WC after rehabilitation and predischarge WC or ejection fraction. Therefore, the selection of patients for cardiac rehabilitation after a myocardial infarction should be based primarily on clinical grounds. Exclusion based on exercise induced angina, ST segment depression or low resting ejection fraction at hospital discharge or at entry in the rehabilitation program is not justified.
本研究的目的是评估与出院前临床检查、静息放射性核素心室造影和症状限制型踏车运动试验相关的数据能否预测近期心肌梗死患者康复计划后是否能达到正常运动能力。研究人群包括141例连续完成3个月训练计划的患者。排除心力衰竭和/或严重心绞痛患者。康复计划包括在3个月内每周进行两次训练课程。工作能力(WC)从出院时的79±17%增加到康复后的105±21%(正常价值)(P<0.001),平均增加33%。95例患者达到了正常的WC。出院前的常规临床评估、静息左心室射血分数、运动诱发心绞痛或ST段压低并不能预测康复后是否能达到正常的WC。与持续低WC的患者相比,出院前WC是康复后正常WC的最佳单一预测指标(正常WC患者为84±15%,持续低WC患者为69±14%,P<0.001)。然而,基线WC低于80%的患者中有49%在康复后达到了正常的WC。康复后WC的变化与出院前WC或射血分数之间未发现相关性。因此,心肌梗死后心脏康复患者的选择应主要基于临床依据。基于运动诱发心绞痛、ST段压低或出院时或进入康复计划时静息射血分数低而排除患者是不合理的。