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卡介苗膀胱灌注治疗后 FDG PET/CT 发现播散性卡介苗感染。

Disseminated Bacillus Calmette-Guérin Infection Detected on FDG PET/CT Following Intravesical Bacillus Calmette-Guérin Therapy.

机构信息

From the Queensland X-Ray, Greenslopes Private Hospital, Greenslopes.

出版信息

Clin Nucl Med. 2020 Jul;45(7):e323-e324. doi: 10.1097/RLU.0000000000003046.

DOI:10.1097/RLU.0000000000003046
PMID:32433172
Abstract

We report the case of a 64-year-old man who presented with back pain, anorexia, and weight loss 9 months following bacillus Calmette-Guérin immunotherapy for high-grade transitional cell carcinoma of the bladder. A FDG PET/CT was performed, which demonstrated osteolysis and intense FDG avidity of the T6/T7 and T8/T9 vertebral endplates. In addition, an aneurysm with FDG-avid soft tissue was present of the distal left common iliac artery. The provisional diagnosis was disseminated bacillus Calmette-Guérin infection, resulting in spondylodiscitis and a mycotic aneurysm. A CT-guided vertebral biopsy confirmed the presence of Mycobacterium tuberculosis DNA on polymerase chain reaction testing.

摘要

我们报告了一例 64 岁男性病例,他在因高级别移行细胞膀胱癌接受卡介苗免疫治疗 9 个月后出现背痛、食欲不振和体重减轻。进行了 FDG PET/CT 检查,显示 T6/T7 和 T8/T9 椎体终板的溶骨性病变和强烈的 FDG 摄取。此外,左侧髂总动脉远端还存在一个伴有 FDG 摄取的软组织的动脉瘤。初步诊断为播散性卡介苗感染,导致脊椎炎和真菌性动脉瘤。CT 引导下的脊柱活检通过聚合酶链反应检测证实存在结核分枝杆菌 DNA。

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Disseminated Bacillus Calmette-Guérin Infection Detected on FDG PET/CT Following Intravesical Bacillus Calmette-Guérin Therapy.卡介苗膀胱灌注治疗后 FDG PET/CT 发现播散性卡介苗感染。
Clin Nucl Med. 2020 Jul;45(7):e323-e324. doi: 10.1097/RLU.0000000000003046.
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Fatal disseminated mycobacterial infection following intravesical bacillus Calmette-Guerin.膀胱内注射卡介苗后发生致命性播散性分枝杆菌感染。
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Tubercular prostatic abscess as a complication of intravesical bacillus Calmette-Guérin immunotherapy.结核性前列腺脓肿作为膀胱内卡介苗免疫治疗的一种并发症。
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Mycotic vascular infections of large arteries with Mycobacterium bovis after intravesical bacillus Calmette-Guérin therapy: case report.卡介苗膀胱内灌注治疗后发生牛分枝杆菌所致的大动脉霉菌性血管感染:病例报告
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