1例膀胱内灌注卡介苗后发生的肉芽肿性肝炎。
A case of granulomatous hepatitis after intravesical bacillus Calmette-Guerin administration.
作者信息
Graziano D A, Jacobs D, Lozano R G, Buck R L
出版信息
J Urol. 1991 Oct;146(4):1118-9. doi: 10.1016/s0022-5347(17)38019-9.
PMID:1895437
Abstract
A 61-year-old man received intravesical bacillus Calmette-Guerin (BCG) as treatment for superficial bladder carcinoma. High spiking relapsing fevers began 39 days after the initial treatment. A liver biopsy revealed noncaseating granuloma. Deoxyribonucleic acid hybridization of the bone marrow was positive for Mycobacterium tuberculosis complex. Pressure exerted to instill the BCG may have favored dissemination.
摘要
一名61岁男性接受膀胱内卡介苗（BCG）治疗浅表性膀胱癌。初始治疗39天后开始出现高热反复发热。肝脏活检显示非干酪样肉芽肿。骨髓的脱氧核糖核酸杂交检测对结核分枝杆菌复合群呈阳性。灌注卡介苗时施加的压力可能有利于其播散。
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