Suppr超能文献

神经外科人群中手术开始时间较晚与并发症发生率的关系:一项前瞻性纵向分析。

Late Surgical Start Time and the Effect on Rates of Complications in a Neurosurgical Population: A Prospective Longitudinal Analysis.

机构信息

Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA.

School of Medicine, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

World Neurosurg. 2020 Aug;140:e328-e342. doi: 10.1016/j.wneu.2020.05.081. Epub 2020 May 17.

Abstract

OBJECTIVE

The after-hours effect on postoperative complications has been poorly studied in the neurosurgical literature. A recent retrospective analysis showed that patients with a surgical start time (SST) between 09:01 pm and 07:00 am had a greater risk of complications. This study used a prospective registry to examine the relationship between SST and postoperative complications in a large neurosurgical population.

METHODS

We performed a prospective longitudinal cohort analysis of all consecutive adult patients admitted to our neurosurgery service between October 1, 2018 and May 1, 2019. Complications were prospectively recorded and classified as surgical or medical. Univariate and multivariate logistic regressions were used to analyze these data.

RESULTS

Eighty-five surgical complications (6.6%) and 110 medical complications (8.6%) resulted from 1285 operations on 1145 patients. Later SST was predictive of complications in the emergent population (odds ratio [OR], 2.28; 95% confidence interval [CI], 1.01-5.15; P = 0.048) but not in the elective population. Extubation in the neurosurgical intensive care unit (NICU) versus the operating room strongly predicted medical complications (OR, 6.91; 95% CI, 3.33-14.34; P < 0.0001). Patients with a later SST were significantly more likely to be extubated in the NICU (P < 0.0001).

CONCLUSIONS

Patients undergoing emergent operations with a later SST were significantly more likely to have a postoperative complication. Patients who were extubated in the NICU versus the operating room were significantly more likely to have a medical complication. Patients were more likely to be extubated in the NICU if they had a later SST; therefore, SST may indirectly be associated with an increase in medical complications.

摘要

目的

术后并发症的“晚班效应”在神经外科学文献中研究甚少。最近的一项回顾性分析显示,手术开始时间(SST)在晚上 9 点 01 分至早上 7 点 00 分之间的患者并发症风险更高。本研究使用前瞻性登记系统,在大型神经外科学人群中研究 SST 与术后并发症之间的关系。

方法

我们对 2018 年 10 月 1 日至 2019 年 5 月 1 日期间收入我们神经外科的所有连续成年患者进行了前瞻性纵向队列分析。前瞻性记录并发症并分类为手术或医疗。使用单变量和多变量逻辑回归分析这些数据。

结果

1145 名患者的 1285 次手术中出现 85 例手术并发症(6.6%)和 110 例医疗并发症(8.6%)。紧急情况下较晚的 SST 与并发症相关(比值比[OR],2.28;95%置信区间[CI],1.01-5.15;P=0.048),但在择期情况下无相关性。神经外科重症监护病房(NICU)与手术室之间的拔管强烈预测医疗并发症(OR,6.91;95%CI,3.33-14.34;P<0.0001)。较晚的 SST 患者更有可能在 NICU 拔管(P<0.0001)。

结论

接受紧急手术且 SST 较晚的患者术后并发症显著增加。在 NICU 而非手术室拔管的患者发生医疗并发症的可能性显著增加。如果 SST 较晚,患者更有可能在 NICU 拔管;因此,SST 可能间接与医疗并发症的增加相关。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验