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肥胖与非肥胖患者在结直肠加速康复外科(ERAS)方案中的结局比较:一项单中心队列研究。

Comparison of Outcomes between Obese and Non-Obese Patients in a Colorectal Enhanced Recovery After Surgery (ERAS) Program: A Single-Center Cohort Study.

机构信息

Division of Digestive Surgery, Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland,

Division of Digestive Surgery, Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland.

出版信息

Dig Surg. 2020;37(5):420-427. doi: 10.1159/000507545. Epub 2020 May 20.

DOI:10.1159/000507545
PMID:32434182
Abstract

INTRODUCTION

Obese patients are considered at increased risk of postoperative adverse events after colorectal surgery.

OBJECTIVE

The objective of the present study was to compare postoperative outcomes between obese and non-obese patients undergoing elective colorectal surgery in an Enhanced Recovery After Surgery (ERAS) program.

METHODS

A retrospective analysis of a prospective cohort including patients who underwent elective colorectal surgery and were included in an ERAS protocol between February 2014 and December 2017 at Geneva University Hospital, Geneva, Switzerland, was performed. Postoperative outcomes of obese and non-obese patients were compared.

RESULTS

Data of 460 patients were analyzed, including 374 (81%) non-obese and 86 (19%) obese patients. Overall, there was no difference in postoperative outcomes between the 2 groups. Among patients undergoing oncologic surgery, obese subjects had a significantly higher rate of conversion to laparotomy (11.9 vs. 2.1%, p = 0.01) and longer time until return of bowel function (2.38 vs. 1.98 days, p = 0.03), without increased morbidity or longer length of stay.

CONCLUSION

Obese and non-obese patients had similar postoperative outcomes after elective colorectal surgery with ERAS management. ERAS can potentially reduce the increased morbidity usually observed in obese patients following elective colorectal surgery.

摘要

简介

肥胖患者在接受结直肠手术后被认为术后不良事件的风险增加。

目的

本研究旨在比较肥胖和非肥胖患者在加速康复外科(ERAS)方案下接受择期结直肠手术后的术后结局。

方法

对 2014 年 2 月至 2017 年 12 月期间在瑞士日内瓦大学医院接受择期结直肠手术并纳入 ERAS 方案的前瞻性队列的患者进行回顾性分析。比较肥胖和非肥胖患者的术后结局。

结果

分析了 460 例患者的数据,包括 374 例(81%)非肥胖患者和 86 例(19%)肥胖患者。总体而言,两组患者的术后结局无差异。在接受肿瘤手术的患者中,肥胖患者中转开腹的比例显著更高(11.9% vs. 2.1%,p = 0.01),且恢复肠道功能的时间更长(2.38 天 vs. 1.98 天,p = 0.03),但发病率或住院时间无增加。

结论

肥胖和非肥胖患者在接受 ERAS 管理的择期结直肠手术后具有相似的术后结局。ERAS 可能会降低肥胖患者在接受择期结直肠手术后通常观察到的增加的发病率。

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