Department of Internal Medicine, Division of Pulmonary and Critical Care, Eastern Virginia Medical School, Norfolk, VA, USA.
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620923237. doi: 10.1177/2324709620923237.
Metastatic cancer that involves the structures of the heart is a rare complication and most commonly diagnosed during postmortem examination. Classically, the development of secondary tumors involves invasion of the pericardium or the myocardium and may disrupt the cardiac conduction system, causing new arrhythmias and heart failure. In this article, we present the case of a 58-year-old female with new diagnosis of ventricular bigeminy, and evidence of cardiac tamponade physiology from direct compression of the right ventricular outflow tract from high-grade carcinoma of the left breast. As oncologic therapies advance and provide more life-prolonging options to patients, recognition of the mass effect of large tumors should be recognized.
转移性癌症累及心脏结构是一种罕见的并发症，大多数情况下是在尸检时诊断出来的。经典地，继发性肿瘤的发展涉及到心包或心肌的侵犯，可能破坏心脏传导系统，导致新的心律失常和心力衰竭。在本文中，我们介绍了一例 58 岁女性的病例，新诊断为室性二联律，并且由于左乳腺癌的高级别癌，直接压迫右心室流出道，出现心脏压塞生理学的证据。随着肿瘤学治疗的进展，为患者提供了更多延长生命的选择，应该认识到大型肿瘤的占位效应。
