Servicio de Otorrinolaringología, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, IDIVAL, Santander, España.
Servicio de Otorrinolaringología, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, IDIVAL, Santander, España.
Acta Otorrinolaringol Esp (Engl Ed). 2020 Jul-Aug;71(4):249-252. doi: 10.1016/j.otorri.2020.02.003. Epub 2020 May 17.
Liver transplantation is the only alternative treatment in patients in end-stage liver function. In many cases the need for liver transplantation is a consequence of the toxic effects of alcohol. The aim of our study was to determine if patients who are candidates for a liver transplant require a systematic exploration of the head and neck to rule out malignant lesions in this area.
All the candidates for a liver transplant, between 2011 and 2017, were included in our study. All of them underwent a systematic exploration of the head and neck by an otolaryngologist to rule out malignancy of the head and neck.
A total of 141 patients were included in our study. In 2 of them (1.3%) a carcinoma of the head and neck was detected (one of the oropharynx and the other of the larynx). Both patients were asymptomatic from an ENT point of view. They were treated with chemoradiotherapy. One of them died during follow-up due to the appearance of a metachronous lung tumour. The other is free of disease 2 years after diagnosis but without having been transplanted. Both patients had a history of smoking and high alcohol intake.
In patients who are candidates for a liver transplant who have a history of smoking and / or high alcohol intake, a pretransplant head and neck study including pharyngo-laryngeal fibroscopy is indicated.
肝移植是肝功能终末期患者的唯一治疗选择。在许多情况下，需要进行肝移植是由于酒精的毒性作用。我们的研究目的是确定是否需要对候选肝移植患者进行头颈部的系统检查，以排除该区域的恶性病变。
我们纳入了所有 2011 年至 2017 年期间的候选肝移植患者。所有患者均由耳鼻喉科医生进行头颈部的系统检查，以排除头颈部恶性肿瘤。
共有 141 名患者纳入本研究。其中 2 名（1.3%）患者发现头颈部癌（1 例为口咽癌，另 1 例为喉癌）。这 2 名患者在耳鼻喉方面均无症状。他们接受了放化疗。其中 1 名患者在随访期间因出现异时性肺肿瘤而死亡。另 1 名患者在诊断后 2 年无疾病，但未进行移植。这 2 名患者均有吸烟和大量饮酒史。
对于有吸烟和/或大量饮酒史的候选肝移植患者，建议在移植前进行头颈部研究，包括咽喉纤维镜检查。
