Radiology, Neurointervention Division, Stanford University School of Medicine, Stanford, California, USA.
Neurosurgery and Radiology, Stanford University School of Medicine, Stanford, California, USA.
J Neurointerv Surg. 2020 Nov;12(11):1132-1136. doi: 10.1136/neurintsurg-2020-016013. Epub 2020 May 20.
Precise delivery of liquid embolic agents (LEAs) remains a challenge in the endovascular treatment of dural arteriovenous fistulae (dAVFs) and cerebral arteriovenous malformations (cAVMs). Despite significant advances in the past decade, LEA reflux and catheter navigability remain shortcomings of current endovascular technology, particularly in small and tortuous arteries. The Scepter Mini dual-lumen balloon microcatheter aims to address these issues by decreasing the distal catheter profile (1.6 French) while allowing for a small (2.2 mm diameter) balloon at its tip.
We report our initial experience with the Scepter Mini in two patients with anterior cranial fossa dAVFs that were treated with transophthalmic artery embolization.
In both patients, the Scepter Mini catheter was able to be safely advanced into the distal ophthalmic artery close to the fistula site, and several centimeters past the origins of the central retinal and posterior ciliary arteries. A single Onyx injection without any reflux resulted in angiographic cure of the dAVF in both cases, and neither patient suffered any vision loss.
These initial experiences suggest that the Scepter Mini represents a significant advance in the endovascular treatment of dAVFs and cAVMs and will allow for safer and more efficacious delivery of LEAs into smaller and more distal arteries while diminishing the risk of LEA reflux.
在硬脑膜动静脉瘘(dAVF)和脑动静脉畸形(cAVM)的血管内治疗中,精确输送液体栓塞剂(LEA)仍然是一个挑战。尽管在过去十年中取得了重大进展,但 LEA 反流和导管可操作性仍然是当前血管内技术的缺点,尤其是在小而曲折的动脉中。Scepter Mini 双腔球囊微导管旨在通过减小远端导管轮廓(1.6 French)来解决这些问题,同时允许在其尖端有一个小的(2.2 毫米直径)球囊。
我们报告了在两名接受经眶动脉栓塞治疗的前颅窝 dAVF 患者中使用 Scepter Mini 的初步经验。
在两名患者中,Scepter Mini 导管都能够安全地进入到接近瘘口的远端眼动脉,并进入到视网膜中央动脉和睫状后动脉的起源部位几厘米处。一次 Onyx 注射没有任何反流,导致在两种情况下 dAVF 的血管造影治愈,并且没有患者出现视力丧失。
这些初步经验表明,Scepter Mini 代表了 dAVF 和 cAVM 血管内治疗的重大进展,它将允许更安全、更有效的将 LEA 输送到更小、更远端的动脉,同时降低 LEA 反流的风险。