Barat Maxime, Boeken Tom, Moussa Nadia, Di Gaeta Alessandro, Déan Carole, Thioun Nicolas, Del Giudice C, Pellerin Olivier, Sapoval Marc
Department of Body and Interventional Radiology, Hôpital Cochin, AP-HP, Université de Paris-Descartes Paris 5, Paris, 75014, France.
Department of Radiology, Hôpital Cochin, AP-HP, 27 rue du Faubourg Saint-Jacques, Paris, 75014, France.
Cardiovasc Intervent Radiol. 2020 Oct;43(10):1498-1504. doi: 10.1007/s00270-020-02518-1. Epub 2020 May 20.
To prospectively evaluate the feasibility and reproducibility of the semiquantitative measurement of the unenhanced area of the prostate by trans-abdominal contrast-enhanced ultrasound (CEUS) performed immediately after prostate artery embolization (PAE) as a prognostic factor of success.
Thirty-nine patients with PAE were prospectively included. They all underwent pre- and post-PAE trans-abdominal prostate CEUS. Two readers independently evaluated the pre- and post-PAE unenhanced area using a semiquantitative method: unenhanced areas were measured on 3 different slices (basis, middle, and apex) and reported to the whole prostate area. The mean of the three measures was reported semiquantitatively in classes of ten percent and quartiles. We evaluated correlation with clinical success, at 3 months after PAE, defined as a > 25% reduction in the International Prostatic Symptoms Score and a Quality of life < 3.
Twenty-three patients who had bilateral PAE were analyzed. Pre-PAE trans-abdominal prostate CEUS showed visible early and marked enhancement of the entire prostate in all patients. After PAE, all patients had a semiquantitatively measured unenhanced area > 25%. The semiquantitative measurement was found to be highly reproducible, with an interclass correlation > 0.8. No correlation was found between the area of unenhanced tissue and clinical success evaluated at 3 months.
Trans-abdominal prostate CEUS performed early after PAE provides reproducible results and is a valuable tool to evaluate unenhanced areas of the prostate.
3, local non random sample.
前瞻性评估经腹对比增强超声（CEUS）在前列腺动脉栓塞术（PAE）后立即测量前列腺未增强区域的半定量方法的可行性和可重复性，以此作为成功的预后因素。
前瞻性纳入39例行PAE的患者。他们均在PAE前后接受经腹前列腺CEUS检查。两名阅片者使用半定量方法独立评估PAE前后的未增强区域：在3个不同层面（基底部、中部和尖部）测量未增强区域，并报告其占整个前列腺区域的比例。将这三个测量值的平均值以10%的类别和四分位数进行半定量报告。我们评估了与临床成功的相关性，PAE后3个月的临床成功定义为国际前列腺症状评分降低>25%且生活质量<3。
分析了23例行双侧PAE的患者。PAE前经腹前列腺CEUS显示所有患者的整个前列腺均有明显的早期和显著增强。PAE后，所有患者的半定量测量未增强区域均>25%。发现半定量测量具有高度可重复性，组内相关系数>0.8。未发现未增强组织区域与3个月时评估的临床成功之间存在相关性。
PAE后早期进行的经腹前列腺CEUS提供了可重复的结果，是评估前列腺未增强区域的有价值工具。
3，局部非随机样本。
