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鼓室成形术中鼓膜鼓室瓣错位导致的医源性胆脂瘤:五例系列病例。

Iatrogenic cholesteatoma originating from a misplaced tympanomeatal flap during tympanoplasty: a series of five patients.

机构信息

Department of Otolaryngology Head, Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weitzmann Street, 6423906, Tel Aviv, Israel.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Eur Arch Otorhinolaryngol. 2020 Dec;277(12):3295-3299. doi: 10.1007/s00405-020-06039-y. Epub 2020 May 20.

Abstract

PURPOSE

To report our experience of a sequence of events that resulted in an iatrogenic cholesteatoma originating from the external auditory canal (EAC) years after tympanoplasty that had included a tympanomeatal flap.

METHODS

Data on the presentation and pathogenesis of iatrogenic cholesteatomas arising from misplaced tympanomeatal flaps during tympanoplasty without mastoidectomy were retrieved from the patients' medical records and analyzed.

RESULTS

Five patients were identified with cholesteatomas involving the EAC. They all had recurrent ear infections and varying degrees of conductive hearing loss. Each patient's past surgical history included one or more tympanoplasties in which an ipsilateral tympanomeatal flap had been raised. None had undergone a mastoidectomy. Two patients presented with small cholesteatomas that had developed over an average of 6.5 years after surgery. Three patients had large cholesteatomas that had developed over an average of 33.7 years after surgery. Clinical presentations and imaging studies suggested a misplaced tympanomeatal flap as the most likely source of cholesteatoma.

CONCLUSION

Tympanomeatal flap misplacement may cause iatrogenic cholesteatoma formation originating from the EAC during tympanoplasty even without mastoidectomy. These cholesteatomas can grow substantially before becoming symptomatic as they extend to and through the mastoid. They may not affect the sound conduction system until late in the course of the disease. Meticulous replacement of tympanomeatal flaps and exercising a high index of suspicion postoperatively can reduce the incidence of this complication.

摘要

目的

报告一系列事件的经验,这些事件导致在鼓室成形术(包括鼓室乳突皮瓣)后多年,外耳道(EAC)出现医源性胆脂瘤。

方法

从患者的病历中检索并分析了在未行乳突切除术的鼓室成形术中因鼓室乳突皮瓣错位而导致医源性胆脂瘤的发生和发病机制的数据。

结果

确定了 5 例涉及 EAC 的胆脂瘤患者。他们都有复发性耳部感染和不同程度的传导性听力损失。每位患者的既往手术史均包括一次或多次鼓室成形术,其中同侧鼓室乳突皮瓣被抬起。均未行乳突切除术。2 例患者表现为小胆脂瘤,平均在手术后 6.5 年发展。3 例患者表现为大胆脂瘤,平均在手术后 33.7 年发展。临床表现和影像学研究提示鼓室乳突皮瓣错位是胆脂瘤最可能的来源。

结论

即使没有乳突切除术,鼓室乳突皮瓣错位也可能导致鼓室成形术中 EAC 出现医源性胆脂瘤形成。这些胆脂瘤在出现症状之前可能会显著生长,因为它们会延伸到并穿过乳突。直到疾病的后期,它们才会影响声音传导系统。仔细替换鼓室乳突皮瓣并在术后保持高度怀疑,可以降低这种并发症的发生率。

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