Ophthalmology Department, Duzce University School of Medicine, 81620, Duzce, Turkey.
Ophthalmology Department, Gazi University School of Medicine, Ankara, Turkey.
Lasers Med Sci. 2021 Mar;36(2):349-356. doi: 10.1007/s10103-020-03038-7. Epub 2020 May 20.
The purpose of this study is to compare two dacryocystorhinostomy (DCR) techniques in epiphora treatment. This study is a prospective randomized trial. Twenty-nine patients presenting persistent epiphora due to primary acquired nasolacrimal duct obstruction (PANDO) were included in the study. Two groups each consisting of 15 eyes were formed. Mechanical transnasal endoscopic DCR (MTE-DCR) was applied to the first group, while transcanalicular dacryocystorhinostomy with multidiode laser (TCML-DCR) techniques is employed in the second group. Follow-up is conducted in the first day, first week, and first month of the dacryocystorhinostomy which is followed by 4-month follow-up period, and results were compared using statistical methods. The main outcome measures were the elimination of epiphora and unrestricted flow of irrigated saline to the nose. Seven patients were male, 22 were female, and the mean age was 39.3 ± 12.5 years. Mean follow-up times were 111.3 ± 10.5 months and 93 ± 2.9 months in group 1 and group 2, respectively. Complete resolution is achieved in group 1, whereas failures stemming from canalicular stenosis and fibrosis at osteotomy site are recorded in two cases in group 2. Occlusion occurred in the fifth month in both cases. Thus, long-term success rates were 100% in the first and 86.6% in the second group (P = 0.483). MTE-DCR is a strong substitute for external DCR. Although TCML-DCR shows promising results, it is far away from becoming the gold standard technique in epiphora treatment.
本研究旨在比较两种治疗溢泪的泪囊鼻腔吻合术(DCR)技术。这是一项前瞻性随机试验。本研究纳入了 29 例因原发性获得性鼻泪管阻塞(PANDO)导致持续性溢泪的患者。将患者分为两组,每组 15 只眼。第一组采用经鼻内镜下机械性泪囊鼻腔吻合术(MTE-DCR),第二组采用经泪小管泪囊鼻腔吻合术联合多二极管激光(TCML-DCR)。术后第 1 天、第 1 周、第 1 个月进行随访,之后进行 4 个月的随访,并采用统计学方法比较结果。主要观察指标为溢泪消除和冲洗盐水无限制流入鼻腔。7 例为男性,22 例为女性,平均年龄为 39.3±12.5 岁。第 1 组和第 2 组的平均随访时间分别为 111.3±10.5 个月和 93±2.9 个月。第 1 组完全缓解,第 2 组有 2 例因吻合口泪小管狭窄和纤维化导致失败。第 2 组 2 例均于第 5 个月发生吻合口阻塞。因此,第 1 组的长期成功率为 100%,第 2 组为 86.6%(P=0.483)。MTE-DCR 是外 DCR 的有力替代方法。虽然 TCML-DCR 显示出良好的效果,但它远未成为治疗溢泪的金标准技术。