Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of General Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Clin Pharm Ther. 2020 Aug;45(4):848-851. doi: 10.1111/jcpt.13180. Epub 2020 May 21.
The botulinum toxin (BoNT) has been widely used for various conditions associated with pain.
Here, we report a case where celiac plexus block (CPB) with BoNT relieved intractable chronic pancreatic pain without complications. CPB was performed at the L1 level under fluoroscopic guidance, and 50 IU BoNT was injected on each side. After 15 weeks, pain was decreased to 0/10 on a visual analogue scale, without opioids or tramadol.
Our case demonstrates the efficacy of CPB with BoNT in intractable pain due to severe chronic pancreatitis.
肉毒杆菌毒素（BoNT）已被广泛用于治疗各种与疼痛相关的疾病。
在这里，我们报告了一例应用 BoNT 的腹腔神经丛阻滞（CPB）成功缓解了一例顽固性慢性胰腺炎疼痛的病例，且无并发症发生。CPB 在透视引导下于 L1 水平进行，每侧注射 50IU BoNT。15 周后，疼痛评分从视觉模拟评分的 10/10 降至 0/10，无需使用阿片类药物或曲马多。
我们的病例证明了 CPB 联合 BoNT 治疗严重慢性胰腺炎引起的顽固性疼痛的有效性。
