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用于肌肉减少症的未来超声生物标志物:弹性成像、超声造影和超声声速成像

Future Ultrasound Biomarkers for Sarcopenia: Elastography, Contrast-Enhanced Ultrasound, and Speed of Sound Ultrasound Imaging.

作者信息

Ivanoski Slavcho, Vasilevska Nikodinovska Violeta

机构信息

Department of Radiology, Special Hospital for Orthopedic Surgery and Traumatology, St. Erazmo - Ohrid, Ss. Cyril and Methodius University of Skopje, Skopje, Macedonia.

Department of Radiology, University Surgical Clinic, St. Naum Ohridski Skopje, Ss. Cyril and Methodius University of Skopje, Skopje, Macedonia.

出版信息

Semin Musculoskelet Radiol. 2020 Apr;24(2):194-200. doi: 10.1055/s-0040-1701630. Epub 2020 May 21.

DOI:10.1055/s-0040-1701630
PMID:32438445
Abstract

Sarcopenia is the advanced and generalized loss of muscle mass and strength among the elderly population and is a cause of adverse outcomes. Methods used for the diagnosis of sarcopenia are either unavailable or expensive in everyday clinical settings. Ultrasound presents an inexpensive, convenient, and available method that offers advantages for the evaluation of skeletal muscle. Muscle quality will probably be the most important factor in defining sarcopenia in the future. Different features of muscle quality, including muscle elasticity, microcirculation and muscle perfusion during rest and physical activity, and the content of intramuscular adipose tissue can be measured using emerging and promising ultrasound techniques such as elastography, contrast-enhanced imaging, and speed of sound ultrasound technology. This article reviews the recent evidence on the use of ultrasound techniques in the assessment of muscle quality and the possibilities for the future evaluation of sarcopenia.

摘要

肌肉减少症是老年人群中肌肉质量和力量的晚期全身性丧失,是不良后果的一个原因。在日常临床环境中,用于诊断肌肉减少症的方法要么不可用,要么费用高昂。超声提供了一种廉价、便捷且可用的方法,对骨骼肌评估具有优势。肌肉质量可能将成为未来定义肌肉减少症的最重要因素。利用诸如弹性成像、对比增强成像和超声声速技术等新兴且有前景的超声技术,可以测量肌肉质量的不同特征,包括肌肉弹性、微循环以及静息和体力活动期间的肌肉灌注,还有肌内脂肪组织的含量。本文综述了超声技术在评估肌肉质量方面的最新证据以及未来评估肌肉减少症的可能性。

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