Chen Shao-Yu, Wang Yao-Wei, Chen Wen-Shiang, Hsiao Ming-Yen
Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Department of Physical Medicine and Rehabilitation, College of Medicine, National Taiwan University, Taipei, Taiwan.
J Med Ultrasound. 2023 Jan 13;31(2):92-100. doi: 10.4103/jmu.jmu_94_22. eCollection 2023 Apr-Jun.
Contrast-enhanced ultrasound (CEUS) uses an intravascular contrast agent to enhance blood flow signals and assess microcirculation in different parts of the human body. Over the past decade, CEUS has become more widely applied in musculoskeletal (MSK) medicine, and the current review aims to systematically summarize current research on the application of CEUS in the MSK field, focusing on 67 articles published between January 2001 and June 2021 in online databases including PubMed, Scopus, and Embase. CEUS has been widely used for the clinical assessment of muscle microcirculation, tendinopathy, fracture nonunions, sports-related injuries, arthritis, peripheral nerves, and tumors, and can serve as an objective and quantitative evaluation tool for prognosis and outcome prediction. Optimal CEUS parameters and diagnostic cut off values for each disease category remain to be confirmed.
超声造影(CEUS)使用血管内造影剂来增强血流信号,并评估人体不同部位的微循环。在过去十年中,CEUS在肌肉骨骼(MSK)医学中的应用越来越广泛,本综述旨在系统总结CEUS在MSK领域应用的当前研究,重点关注2001年1月至2021年6月期间发表在包括PubMed、Scopus和Embase在内的在线数据库中的67篇文章。CEUS已广泛用于肌肉微循环、肌腱病、骨折不愈合、运动相关损伤、关节炎、周围神经和肿瘤的临床评估,并可作为预后和结局预测的客观定量评估工具。每种疾病类别的最佳CEUS参数和诊断临界值仍有待确定。