Cooper J D, Turnell D C, Green B, Verillon F
Department of Biochemistry, Coventry and Warwickshire Hospital, U.K.
J Chromatogr. 1988 Dec 2;456(1):53-69. doi: 10.1016/0021-9673(86)80006-1.
The development of the sample preparation process, the automated sequential trace enrichment of dialysates, in association with a cartesian robotic sampler is described. The system has been applied to the total automation of the preparation of biological samples and high-performance liquid chromatographic analysis. Concepts of the technique are reported together with an examination of its application to free and total analyte estimation. Examples of chromatographic separations obtained from the preparation of a variety of different analytes and sample materials are given.
本文描述了与笛卡尔机器人采样器相关的样品制备过程——透析液的自动连续痕量富集的发展情况。该系统已应用于生物样品制备和高效液相色谱分析的全自动化。报告了该技术的概念，并对其在游离和总分析物估计中的应用进行了研究。给出了从各种不同分析物和样品材料制备中获得的色谱分离示例。
