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High-performance liquid chromatographic analysis of the by-products of the synthesis of ethynylestradiol, mestranol, 17 alpha-hydroxy-progesterone caproate and 17 alpha-hydroxy-6-dehydroprogesterone acetate.

作者信息

Levtchenko N K, Osokin D M, Torgov I V, Arzamastzev A P, Sokolova T M, Tuguntaev G I

机构信息

M. M. Shemyakin Institute of Bioorganic Chemistry, Academy of Sciences of the U.S.S.R., Moscow.

出版信息

J Chromatogr. 1988 Dec 16;456(2):427-30. doi: 10.1016/0021-9673(86)80043-7.

DOI:10.1016/0021-9673(86)80043-7
PMID:3243879
Abstract
摘要

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1
High-performance liquid chromatographic analysis of the by-products of the synthesis of ethynylestradiol, mestranol, 17 alpha-hydroxy-progesterone caproate and 17 alpha-hydroxy-6-dehydroprogesterone acetate.炔雌醇、炔诺醇、己酸17α-羟基孕酮和醋酸17α-羟基-6-脱氢孕酮合成副产物的高效液相色谱分析
J Chromatogr. 1988 Dec 16;456(2):427-30. doi: 10.1016/0021-9673(86)80043-7.
2
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Method for determining residues of mestranol and ethynylestradiol in foliage, soil, and water samples.测定树叶、土壤和水样中炔雌醇甲醚和乙炔雌二醇残留量的方法。
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Identification of autoxidation and photodegradation products of ethynylestradiol by on-line HPLC-NMR and HPLC-S.通过在线高效液相色谱-核磁共振联用技术和高效液相色谱-质谱联用技术鉴定乙炔雌二醇的自氧化和光降解产物。
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Ketonitrophenols from mestranol and related compounds.炔雌醇及相关化合物中的酮硝基酚。
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Maintenance of pregnancy in castrated rabbits by 17-alpha-hydroxy-progesterone caproate and by progesterone.
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Treatment of human diabetic pregnancies with estradiol valerate and 17 alpha-hydroxyprogesterone 17-n-caproate.用戊酸雌二醇和17α-羟孕酮17-正己酸酯治疗人类糖尿病妊娠。
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Synthesis of compounds of potential value in the radioimmunoassay of 17 alpha-ethynylestradiol and mestranol.17α-乙炔雌二醇和炔雌醇放射免疫分析中具有潜在价值的化合物的合成。
Steroids. 1974 Feb;23(2):173-83. doi: 10.1016/0039-128x(74)90150-0.

引用本文的文献

1
Simultaneous quantitation of 17alpha-hydroxyprogesterone caproate, 17alpha-hydroxyprogesterone and progesterone in human plasma using high-performance liquid chromatography-mass spectrometry (HPLC-MS/MS).使用高效液相色谱-质谱联用仪(HPLC-MS/MS)同时定量测定人血浆中己酸17α-羟孕酮、17α-羟孕酮和孕酮。
J Pharm Biomed Anal. 2008 Dec 1;48(4):1174-80. doi: 10.1016/j.jpba.2008.08.024. Epub 2008 Aug 29.
2
Development and validation of a high-performance liquid chromatography-mass spectrometric assay for the determination of 17alpha-hydroxyprogesterone caproate (17-OHPC) in human plasma.用于测定人血浆中己酸17α-羟孕酮(17-OHPC)的高效液相色谱-质谱分析方法的开发与验证
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):141-7. doi: 10.1016/j.jchromb.2007.05.028. Epub 2007 Jun 2.