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肺血栓栓塞症作为COVID-19患者临床病情恶化的潜在原因;一篇评论

Pulmonary Thromboembolism as a Potential Cause of Clinical Deterioration in COVID-19 Patients; a Commentary.

作者信息

Safari Saeed, Mehrani Mehdi, Yousefifard Mahmoud

机构信息

Proteomic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Emergency department, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Arch Acad Emerg Med. 2020 Apr 19;8(1):e52. eCollection 2020.

PMID:32440663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7212069/
Abstract

Although the findings of some studies have been indicative of the direct relationship between the severity of clinical findings and imaging, reports have been published regarding inconsistency of clinical findings with imaging and laboratory evidence. Physicians treating these patients frequently report cases in which patients, sometimes in the recovery phase and despite improvements in imaging indices, suddenly deteriorate and in some instances suddenly expire. This letter aimed to draw attention to the role of pulmonary thromboembolism as a potential and possible cause of clinical deterioration in covid-19 patients.

摘要

尽管一些研究结果表明临床症状的严重程度与影像学表现之间存在直接关系,但也有关于临床症状与影像学及实验室证据不一致的报告发表。治疗这些患者的医生经常报告这样的病例:患者有时在康复阶段,尽管影像学指标有所改善,但病情突然恶化,在某些情况下甚至突然死亡。这封信旨在提请注意肺血栓栓塞作为新冠病毒肺炎患者临床病情恶化的一个潜在且可能的原因所起的作用。

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本文引用的文献

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Radiol Cardiothorac Imaging. 2020 Mar 16;2(2):e200067. doi: 10.1148/ryct.2020200067. eCollection 2020 Apr.
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Clinical characteristics and laboratory indicator analysis of 67 COVID-19 pneumonia patients in Suzhou, China.中国苏州 67 例新冠肺炎患者的临床特征和实验室指标分析。
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Incidence of thrombotic complications in critically ill ICU patients with COVID-19.COVID-19 重症监护病房危重症患者的血栓并发症发生率。
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COVID-19 in a designated infectious diseases hospital outside Hubei Province, China.中国湖北省外指定传染病医院的 COVID-19 疫情。
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Clin Chem Lab Med. 2020 Jun 25;58(7):1116-1120. doi: 10.1515/cclm-2020-0188.
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Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.
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