Firoozgar Clinical Research Development Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
ENT and Head and Neck Research Center, The Five Senses Institute, Hazrat Rasoul Hospital, Iran University of Medical Sciences, Tehran, Iran.
Rhinology. 2020 Jun 1;58(3):208-212. doi: 10.4193/Rhin19.258.
Chronic rhinosinusitis (CRS) is a common chronic inflammatory disease. Endoscopic sinus surgery is recommended as a standard method when medical treatment fails. The effectiveness of various complementary surgical methods such as endoscopic partial middle-turbinectomy is controversial in the improvement of CRS symptoms in these patients. This study aimed to investigate the effect of endoscopic partial middle-turbinectomy on the quality of life (QOL) of patients with chronic rhinosinusitis and nasal polyps (CRSwNP) in Iran.
Ninety patients with CRSwNP of grades 3 and 4 were randomly assigned to either an intervention (45 patients) or control group (45 patients). In the control group, endoscopic sinus surgery without middle turbinectomy was performed and in the intervention group, endoscopic partial middle-turbinectomy was performed in addition to endoscopic sinus surgery. To evaluate the outcomes, the SNOT-22 QOL questionnaire was used, and the results were analyzed using SPSS version 24.
Most of the patients were male and had a mean age of 39 years. The mean SNOT-22 QOL questionnaire scores were 49.13 ± 16.72 and 52.51 ± 16.95 before surgery in the control and intervention groups respectively, which did not show any significant difference. In contrast, after endoscopic surgery these scores changed to 28.46 ± 12.38 and 11.13 ± 5.55 in the control and intervention groups, respectively and there was a significant difference between both groups. Although there was a significant improvement in both groups, the patients in the intervention group experienced more improvement than the control group (41.4 (± 16.46)) vs 30.7 (±18.27), respectively CONCLUSION: According to this study, it appears that the use of endoscopic partial middle-turbinectomy in addition to endoscopic sinus surgery improves CRS symptoms and the QOL of patients compared with endoscopic sinus surgery alone.
慢性鼻-鼻窦炎（CRS）是一种常见的慢性炎症性疾病。当药物治疗失败时，推荐进行内镜鼻窦手术。在这些患者中，内镜下鼻甲部分切除术等各种补充性手术方法对改善 CRS 症状的有效性存在争议。本研究旨在探讨内镜下鼻甲部分切除术对伊朗慢性鼻-鼻窦炎伴鼻息肉（CRSwNP）患者生活质量（QOL）的影响。
将 90 例 CRSwNP 3 级和 4 级患者随机分为干预组（45 例）和对照组（45 例）。对照组行内镜鼻窦手术，不切除鼻甲；干预组在进行内镜鼻窦手术的同时行鼻甲部分切除术。采用 SNOT-22 生活质量问卷评估疗效，采用 SPSS 24 版进行数据分析。
大多数患者为男性，平均年龄 39 岁。术前对照组和干预组的 SNOT-22 生活质量问卷评分分别为 49.13±16.72 和 52.51±16.95，差异无统计学意义。相比之下，内镜手术后两组评分分别变为 28.46±12.38 和 11.13±5.55，差异有统计学意义。虽然两组均有显著改善，但干预组患者的改善程度大于对照组（41.4（±16.46））vs 30.7（±18.27））。
根据本研究，与单纯内镜鼻窦手术相比，内镜下鼻甲部分切除术联合内镜鼻窦手术可改善 CRS 症状和患者的 QOL。
