Wainer Pedro, Saavedra Federico, Tagliapietra Valeria, Abeledo Daiana, Migliore Daniela, Lapadula Pablo, Pryluka Daniel, Lopez Macchi Gonzalo, Diez Eduardo, Gnocchi César
Servicio de Clínica Médica, Sanatorio Otamendi, Argentina. E-mail:
Servicio de Clínica Médica, Sanatorio Otamendi, Argentina.
Medicina (B Aires). 2020;80(3):193-196.
The first case of coronavirus (COVID-19) infection in Argentina was reported in Buenos Aires on March 3rd, 2020, in a patient who arrived from Milan. The aim of this study is to describe the clinical characteristics and course of illness of patients infected with Covid-19 that were hospitalized in a private clinical setting during March 2020. Sixty three patients suspected of COVID-19 infection, were admitted to our hospital during March 2020. Twenty six of these subjects were diagnosed positive by the RT-PCR for SARS Cov-2 in a nasopharyngeal swab specimen. We recorded data about epidemiological characteristics, clinical signs and symptoms, in addition to comorbidities, laboratory and radiological studies were done. The median age was 40 years (SD ± 15 years); there was an equal number of men and women; all the patients but one were coming from abroad; the most common symptom was fever (24/26 cases) and lymphopenia (n = 8). We found that there were patients in whom fever disappeared within the first 72h (n = 17) and another group in which the fever lasted six or more days (n = 7). One patient out of 26 died. The population of our study was young and almost all were imported cases, in alinement with the stage of the epidemic at the time when the study was conducted. We observed that there were two patterns in the fever curve but the persistence of it did not lead to a worse prognosis. Larger population studies are required in order to confirm these clinical findings.
2020年3月3日，阿根廷在布宜诺斯艾利斯报告了首例冠状病毒（COVID-19）感染病例，患者来自米兰。本研究的目的是描述2020年3月期间在一家私立诊所住院的COVID-19感染患者的临床特征和病程。2020年3月，63名疑似COVID-19感染的患者被收治入院。其中26名患者的鼻咽拭子标本经RT-PCR检测确诊为SARS-CoV-2阳性。我们记录了流行病学特征、临床体征和症状的数据，此外还记录了合并症情况，并进行了实验室和影像学检查。中位年龄为40岁（标准差±15岁）；男女数量相等；除1名患者外，所有患者均来自国外；最常见的症状是发热（24/26例）和淋巴细胞减少（n = 8）。我们发现，有些患者在最初72小时内发热消失（n = 17），另一组患者发热持续6天或更长时间（n = 7）。26名患者中有1名死亡。我们研究的人群较为年轻，几乎都是输入性病例，这与研究开展时的疫情阶段相符。我们观察到发热曲线有两种模式，但发热持续并未导致更差的预后。需要开展更大规模的人群研究以证实这些临床发现。
