丁苯酞对分水岭脑梗死患者血流动力学有影响吗？：一项系统评价与Meta分析方案
Does butylphthalide affect on hemodynamics in patients with watershed stroke?: A protocol of systematic review and meta-analysis.
作者信息
Jia Li-Na, Zhang Ya-Juan, Ma Rong, Song You
机构信息
Department of Neurology, The Central Hospital of Jia Mu Si City, Jiamusi.
Department of Neurology, First Affiliated Hospital of Jiamusi University, Jiamusi, China.
出版信息
Medicine (Baltimore). 2020 May;99(20):e20151. doi: 10.1097/MD.0000000000020151.
BACKGROUND
This study will specifically investigate the effect of butylphthalide on hemodynamics in patients with watershed stroke (WS).
METHODS
We will search the following databases from their inceptions to the March 1, 2020: Cochrane Library, MEDLINE, EMBASE, PsycINFO, Web of Science, Cumulative Index to Nursing and Allied Health Literature, and China National Knowledge Infrastructure. All relevant randomized controlled trials on exploring the effect of butylphthalide on hemodynamics in patients with WS will be considered for inclusion. No language limitation will be imposed to this study. All study quality will be checked using Cochrane risk of bias tool. RevMan 5.3 software will be utilized for data analysis.
RESULTS
This study will summarize the latest evidence to investigate the effect of butylphthalide on hemodynamics in patients with WS.
CONCLUSION
Findings from this study will provide theoretical basis of butylphthalide on hemodynamics in patients with WS for clinician and future research.
DISSEMINATION AND ETHICS
This study is carried out based on the published data, thus, no ethical approval is required. We will submit this study to a peer-reviewed journal for publication.
SYSTEMATIC REVIEW REGISTRATION
INPLASY 202030006.
背景
本研究将专门调查丁苯酞对分水岭脑梗死（WS）患者血流动力学的影响。
方法
我们将检索以下数据库自建库至2020年3月1日的数据：Cochrane图书馆、MEDLINE、EMBASE、PsycINFO、科学引文索引、护理学与健康相关文献累积索引以及中国知网。所有探讨丁苯酞对WS患者血流动力学影响的相关随机对照试验都将被纳入考虑。本研究不设语言限制。所有研究质量将使用Cochrane偏倚风险工具进行检查。将使用RevMan 5.3软件进行数据分析。
结果
本研究将总结最新证据，以调查丁苯酞对WS患者血流动力学的影响。
结论
本研究结果将为临床医生和未来研究提供丁苯酞对WS患者血流动力学影响的理论依据。
传播与伦理
本研究基于已发表的数据进行，因此无需伦理批准。我们将把本研究提交给同行评审期刊发表。
系统评价注册
INPLASY 202030006。
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