Ren Runyuan, Tang Guangjun, Tang Chenjian, Zhang Jiayuan, Xiao Xiao, Zhang Qi
Chengdu university of traditional Chinese medicine, Chengdu, Sichuan province, China.
Medicine (Baltimore). 2020 May;99(20):e20242. doi: 10.1097/MD.0000000000020242.
Knee osteoarthritis (KOA) is a disabling joint disease with an increasingly prevalence among the older individuals. Tai Chi, one of the ancient meditative movements, has been recognized to have clinical benefits for KOA. We aim to evaluate the efficacy and safety of Tai Chi for patients with KOA through this systematic review.
Five English databases (Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, AMED, and CINAHL), 4 Chinese databases (CBM, CNKI, CQVIP, and Wanfang), and 5 clinical trial registration databases (ClinicalTrials.gov, ANZCTR, EU-CTR, ChiCTR, and ICTRP) will be searched from establishment of the database until November 31, 2019. Grey literature will be searched in SIGLE, Grey Net, Microsoft Academic, Google Scholar, Open Aire, World Wide Science.org, and WorldCat. There will be no restrictions on language. The randomized controlled trials of Tai Chi training for patients with KOA will be included. The primary outcome will be assessed according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Meta-analysis will be conducted with the use of RevMan 5.3. The specific process will refer to the Cochrane Handbook 5.1 for Systematic Review.
High-quality synthesis of current evidence on the efficacy and safety of Tai Chi training for KOA will be provided in this study.
This systematic review aims to present evidence for whether Tai Chi training is an effective intervention which can improve both physical condition and life quality in patients suffering KOA.
膝关节骨关节炎（KOA）是一种致残性关节疾病，在老年人中的患病率日益增加。太极拳作为一种古老的冥想运动，已被认为对KOA具有临床益处。我们旨在通过本系统评价评估太极拳对KOA患者的疗效和安全性。
将检索5个英文数据库（Cochrane对照试验中心注册库（CENTRAL）、医学期刊数据库（MEDLINE）、荷兰医学文摘数据库（EMBASE）、联合和补充医学数据库（AMED）以及护理学与健康领域数据库（CINAHL））、4个中文数据库（中国生物医学文献数据库（CBM）、中国知网（CNKI）、维普资讯网（CQVIP）和万方数据库）以及5个临床试验注册数据库（美国国立医学图书馆临床试验注册库（ClinicalTrials.gov）、澳大利亚和新西兰临床试验注册库（ANZCTR）、欧盟临床试验注册库（EU-CTR）、中国临床试验注册中心（ChiCTR）和国际临床试验注册平台（ICTRP）），检索时间从各数据库建立至2019年11月31日。还将在灰色文献数据库（SIGLE）、Grey Net、微软学术搜索、谷歌学术搜索、Open Aire、世界科学网（World Wide Science.org）和世界书目数据库（WorldCat）中检索灰色文献。语言不限。将纳入KOA患者太极拳训练的随机对照试验。主要结局将根据西安大略和麦克马斯特大学骨关节炎指数（WOMAC）进行评估。将使用RevMan 5.3进行荟萃分析。具体过程将参考Cochrane系统评价手册5.1。
本研究将提供关于太极拳训练对KOA疗效和安全性的当前证据的高质量综合分析。
本系统评价旨在提供证据，证明太极拳训练是否为一种有效的干预措施，可改善KOA患者的身体状况和生活质量。
