Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Department of Neurology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
J Parkinsons Dis. 2020;10(3):1143-1151. doi: 10.3233/JPD-201930.
Social functioning is crucial for the determinants of Parkinson's disease (PD) with dementia; however, there is no social functioning scale applicable to PD.
This study aimed to develop a social functioning scale specific to PD (PDSFS) and provide a cut-off score to improve diagnosis accuracy.
The items were developed through literature, interview patients, and PD expertise. After the pilot study, one hundred fifty-seven patients and 74 healthy participants were enrolled and completed the Mini-Mental State Examination, Clock Drawing Test, Activities of Daily Living, Neuropsychiatric Inventory, Adaptive Behavior Assessment System-Second Edition (ABAS-II) and part III of the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS).
The final PDSFS has 23 items. The exploratory factor analysis revealed three factors, including "Family Life, Hobbies and Self-Care", "Interpersonal Relationship and Recreational Leisure", and "Social Bond". The internal consistency coefficient was 0.883, and the test-retest reliability was 0.774, respectively. The total score of the PDSFS was significantly related to the total score of ABAS-II (r = 0.609, p < 0.001), and was not correlated with the third part of MDS-UPDRS (p = 0.736). A significant intergroup difference was found (p < 0.001), and the healthy controls had the highest PDSFS score, followed by non-demented PD and PD dementia. The optimal cut-off score for PD patients with dementia was 39 (sensitivity: 0.735; specificity: 0.857).
PDSFS is a practical and psychometrically sound tool to access the social functioning of the PD population.
社会功能对于帕金森病（PD）伴痴呆的决定因素至关重要；然而，目前尚无适用于 PD 的社会功能量表。
本研究旨在开发一种特定于 PD 的社会功能量表（PDSFS），并提供一个截断分数以提高诊断准确性。
通过文献、访谈患者和 PD 专业知识开发项目。在试点研究之后，纳入了 157 名患者和 74 名健康参与者，并完成了简易精神状态检查、画钟试验、日常生活活动能力量表、神经精神问卷、适应行为评估系统第二版（ABAS-II）和运动障碍协会赞助的统一帕金森病评定量表第三部分修订版（MDS-UPDRS）。
最终的 PDSFS 有 23 个项目。探索性因子分析显示，该量表包含三个因子，分别为“家庭生活、爱好和自我护理”、“人际关系和娱乐休闲”和“社会联系”。内部一致性系数为 0.883，重测信度为 0.774。PDSFS 总分与 ABAS-II 总分显著相关（r=0.609，p<0.001），与 MDS-UPDRS 第三部分不相关（p=0.736）。组间差异有统计学意义（p<0.001），健康对照组的 PDSFS 得分最高，其次是非痴呆 PD 组和 PD 痴呆组。PD 痴呆患者的最佳截断分数为 39（灵敏度：0.735；特异性：0.857）。
PDSFS 是一种实用且具有良好心理测量学特性的工具，可用于评估 PD 人群的社会功能。
