Zhavoronkov A A
Arkh Patol. 1977;39(3):83-91.
Concepts of nonskeletal forms of fluorosis are set forth in the light of the author's own investigations and reports in the available literature. Descriptions of pathology of the central nervous system, skeletal musculature, stomach, liver, kidney, cardiovascular system, retina, and the skin are presented. The evidences obtained indicate that disturbances in soft tissues in chronic intoxication with fluorine develop early, usually long before the onset of typical changes in teeth and skeletal bones; these changes characterize the preskeletal phase of fluorosis.
根据作者自身的调查以及现有文献中的报告,阐述了非骨骼型氟中毒的相关概念。文中介绍了中枢神经系统、骨骼肌、胃、肝脏、肾脏、心血管系统、视网膜及皮肤的病理学特征。所获证据表明,慢性氟中毒时软组织的病变出现较早,通常远在牙齿和骨骼出现典型变化之前;这些变化是氟中毒骨骼前期的特征。