Nagpal K C, Asdourian G K, Goldbaum M H, Raichand M, Goldberg M F
Arch Ophthalmol. 1977 May;95(5):808-11. doi: 10.1001/archopht.1977.04450050086008.
Sixty-five patients with hemoglobins AS, SC, and SS were investigated in a masked fashion. We observed a statistically significant positive correlation between the severity of conjunctival sickling signs and the counts of irreversibly sickled cells in each hemoglobinopathy group. We also observed a statistically significant positive correlation between the severity of the conjunctival vasculopathy and the percentage of sickle hemoglobin in the total group of patients with hemoglobins AS, SC, and SS.
对65例血红蛋白AS、SC和SS患者进行了盲法研究。我们观察到,在每个血红蛋白病组中,结膜镰状化体征的严重程度与不可逆镰状细胞计数之间存在统计学上显著的正相关。我们还观察到,在血红蛋白AS、SC和SS患者的总群体中,结膜血管病变的严重程度与镰状血红蛋白百分比之间存在统计学上显著的正相关。