Koren David E, Scarsi Kimberly K, Farmer Eric K, Cha Agnes, Adams Jessica L, Pandit Neha Sheth, Chang Jennifer, Scott James, Hardy W David
Temple University Hospital, Philadelphia, Pennsylvania.
Department of Pharmacy Practice and Science, University of Nebraska Medical Center College of Pharmacy, Omaha.
Clin Infect Dis. 2020 May 23;70(11):2241-2246. doi: 10.1093/cid/ciz792.
Persons living with human immunodeficiency virus (HIV) and others receiving antiretrovirals are at risk for medication errors during hospitalization and at transitions of care. These errors may result in adverse effects or viral resistance, limiting future treatment options. A range of interventions is described in the literature to decrease the occurrence or duration of medication errors, including review of electronic health records, clinical checklists at care transitions, and daily review of medication lists. To reduce the risk of medication-related errors, antiretroviral stewardship programs (ARVSPs) are needed to enhance patient safety. This call to action, endorsed by the Infectious Diseases Society of America, the HIV Medicine Association, and the American Academy of HIV Medicine, is modeled upon the success of antimicrobial stewardship programs now mandated by the Joint Commission. Herein, we propose definitions of ARVSPs, suggest resources for ARVSP leadership, and provide a summary of published, successful strategies for ARVSP that healthcare facilities may use to develop locally appropriate programs.
感染人类免疫缺陷病毒(HIV)的患者以及其他接受抗逆转录病毒药物治疗的人在住院期间和护理转接过程中存在用药错误的风险。这些错误可能导致不良反应或病毒耐药性,限制未来的治疗选择。文献中描述了一系列干预措施,以减少用药错误的发生或持续时间,包括审查电子健康记录、护理转接时的临床检查表以及每日审查用药清单。为降低用药相关错误的风险,需要抗逆转录病毒管理计划(ARVSPs)来提高患者安全性。这一行动呼吁得到了美国传染病学会、HIV医学协会和美国HIV医学学会的认可,它借鉴了目前由联合委员会强制实施的抗菌药物管理计划的成功经验。在此,我们提出ARVSPs的定义,建议ARVSP领导层的资源,并总结已发表的、成功的ARVSP策略,医疗机构可利用这些策略制定适合当地的计划。