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院外心脏骤停后冠状动脉手术与生存的社会经济差异:一项丹麦全国性研究。

Socioeconomic differences in coronary procedures and survival after out-of-hospital cardiac arrest: A nationwide Danish study.

作者信息

Møller Sidsel, Wissenberg Mads, Kragholm Kristian, Folke Fredrik, Hansen Carolina Malta, Ringgren Kristian B, Andersen Julie, Barcella Carlo, Lippert Freddy, Køber Lars, Gislason Gunnar, Gerds Thomas Alexander, Torp-Pedersen Christian

机构信息

Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.

Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark; Copenhagen Emergency Medical Services, University of Copenhagen, Denmark.

出版信息

Resuscitation. 2020 Aug;153:10-19. doi: 10.1016/j.resuscitation.2020.05.022. Epub 2020 May 22.

DOI:10.1016/j.resuscitation.2020.05.022
PMID:32446792
Abstract

AIM

It remains unclear whether socioeconomic differences exist in post-resuscitation care in out-of-hospital cardiac arrests (OHCA). We aimed to examine socioeconomic differences in coronary procedures and survival after OHCA.

METHODS

OHCA patients ≥30 years of cardiac cause with a hospital admission from the Danish Cardiac Arrest Registry, 2001-2014, were divided according to quartiles of household income (lowest, low, high, highest). Associations of income, coronary procedures and 30-day survival were examined by age-standardized incidence rates and incidence rate ratios (IRR), and by logistic regression.

RESULTS

A total of 6105 patients were included. Higher-income patients were younger, males and had less comorbidity-burden. Higher-income patients had higher incidence rates for coronary angiographies both day 0-1 and day 2-7 after OHCA (day 0-1: highest: IRR 1.79, 95%CI 1.46-2.21; high: IRR 1.28, 95%CI 1.10-1.51; low: IRR 1.05, 95%CI 0.90-1.23), compared to lowest. Fifty-four percentage of the patients undergoing a coronary angiography received percutaneous-coronary-intervention or coronary-artery-bypass-grafting with no difference among three of the four groups, but lower IRR in low-income patients (IRR 0.74, 95%CI 0.61-0.89) compared to lowest. Higher-income patients had also higher odds for 30-day survival compared to lowest, both in patients with (highest: OR 1.61, 95%CI 1.12-2.32; high: OR 1.13, 95%CI 0.80-1.60; low: OR 1.14, 95%CI 0.81-1.61) and without (highest: OR 2.54, 95%CI 1.83-3.53; high: OR 1.41, 95%CI 1.06-1.87; low: OR 1.12, 95%CI 0.86-1.47) coronary angiography day 0-1.

CONCLUSION

Higher-income patients were found associated with more performed coronary angiographies after OHCA, and higher odds for 30-day survival.

摘要

目的

院外心脏骤停(OHCA)复苏后护理中是否存在社会经济差异仍不明确。我们旨在研究OHCA后冠状动脉手术和生存率方面的社会经济差异。

方法

将2001年至2014年丹麦心脏骤停登记处收治的≥30岁心脏病因的OHCA患者,根据家庭收入四分位数(最低、低、高、最高)进行分组。通过年龄标准化发病率和发病率比(IRR)以及逻辑回归分析来研究收入、冠状动脉手术和30天生存率之间的关联。

结果

共纳入6105例患者。高收入患者更年轻,男性居多,合并症负担较轻。OHCA后第零天至第一天和第二天至第七天,高收入患者冠状动脉造影的发病率均高于低收入患者(第零天至第一天:最高组:IRR 1.79,95%CI 1.46 - 2.21;高收入组:IRR 1.28,95%CI 1.10 - 1.51;低收入组:IRR 1.05,95%CI 0.90 - 1.23)。接受冠状动脉造影的患者中有54%接受了经皮冠状动脉介入治疗或冠状动脉搭桥术,四组中的三组之间无差异,但低收入患者的发病率比低于最低收入组(IRR 0.74,95%CI 0.61 - 0.89)。无论在第零天至第一天接受冠状动脉造影的患者(最高组:OR 1.61,95%CI 1.12 - 2.32;高收入组:OR 1.13,95%CI 0.80 - 1.60;低收入组:OR

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