Lagedal Rickard, Jonsson Martin, Elfwén Ludvig, Smekal David, Nordberg Per, James Stefan, Rubertsson Sten
Department of Surgical Sciences/Anesthesiology and Intensive Care Medicine, Uppsala University, Sweden.
Department of Medicine, Center for Resuscitation Science, Karolinska Institute, Solna, Sweden.
Resuscitation. 2020 Nov;156:35-41. doi: 10.1016/j.resuscitation.2020.08.016. Epub 2020 Aug 25.
Low socioeconomic status has been associated with worse outcome after cardiac arrest. This study aims to investigate if patients´ income influences the probability to receive early coronary angiography in out-of-hospital cardiac arrest (OHCA) patients.
In this nationwide retrospective observational study, 3906 OHCA patients admitted alive and registered in the Swedish Registry for Cardiopulmonary Resuscitation were included. Individual data on income and educational level, prehospital parameters, coronary angiography results and comorbidity were linked from SWEDEHEART and other national registers.
Patients were divided into quarters depending on their income level. In the unadjusted model there was a strong correlation between income level and rate of early coronary angiography where 35.5% of patients in the highest income quarters received early angiography compared to 15.4% in the lowest income quarters. When adjusting for educational level, sex, age, comorbidity and hospital type, there were still higher chance of receiving early coronary angiography with increasing income, OR 1.31 (CI 1.01-1.68) and 1.67 (CI 1.29-2.16) for the two highest income quarters respectively compared to the lowest income quarter. When adding potential mediators to the model (first recorded ECG rhythm by the EMS, location, response time, bystander cardiopulmonary resuscitation and if the arrest was witnessed) no difference in early angiography related to income level where found. The main mediator was first recorded ECG rhythm.
Income level is associated with the probability to undergo early coronary angiography in OHCA patients. This association seems to be mediated by the initial ECG rhythm.
社会经济地位较低与心脏骤停后较差的预后相关。本研究旨在调查患者收入是否会影响院外心脏骤停(OHCA)患者接受早期冠状动脉造影的可能性。
在这项全国性回顾性观察研究中,纳入了3906例存活入院并登记在瑞典心肺复苏登记处的OHCA患者。来自瑞典心脏注册研究(SWEDEHEART)和其他国家登记处的个人收入、教育水平、院前参数、冠状动脉造影结果及合并症数据被关联起来。
根据收入水平将患者分为四组。在未调整模型中,收入水平与早期冠状动脉造影率之间存在很强的相关性,最高收入组中有35.5%的患者接受了早期造影,而最低收入组中这一比例为15.4%。在对教育水平、性别、年龄、合并症和医院类型进行调整后,随着收入增加,接受早期冠状动脉造影的可能性仍然更高,与最低收入组相比,最高的两个收入组的比值比分别为1.31(95%置信区间1.01 - 1.68)和1.67(95%置信区间1.29 - 2.16)。当在模型中加入潜在中介因素(急救医疗服务首次记录的心电图节律、地点、反应时间、旁观者心肺复苏以及心脏骤停是否被目击)后,未发现与收入水平相关的早期造影差异。主要中介因素是首次记录的心电图节律。
收入水平与OHCA患者接受早期冠状动脉造影的可能性相关。这种关联似乎由初始心电图节律介导。