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Riluzole prescribing, uptake and treatment discontinuation in people with amyotrophic lateral sclerosis in Scotland.

作者信息

Jayaprakash Kiran, Glasmacher Stella A, Pang Bernard, Beswick Emily, Mehta Arpan R, Dakin Rachel, Newton Judith, Chandran Siddharthan, Pal Suvankar

机构信息

Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.

Anne Rowling Regenerative Neurology Clinic, Royal Infirmary, Edinburgh, UK.

出版信息

J Neurol. 2020 Aug;267(8):2459-2461. doi: 10.1007/s00415-020-09919-9. Epub 2020 May 23.

DOI:10.1007/s00415-020-09919-9
PMID:32447548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7359150/
Abstract
摘要

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本文引用的文献

1
Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort.肌萎缩侧索硬化症/运动神经元病临床表型的识别与结局:澳大利亚国家运动神经元病观察队列研究
BMJ Open. 2016 Sep 30;6(9):e012054. doi: 10.1136/bmjopen-2016-012054.
2
A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?回顾力鲁唑治疗肌萎缩侧索硬化症的作用机制和临床疗效:在过去十年中我们学到了什么?
CNS Neurosci Ther. 2011 Feb;17(1):4-31. doi: 10.1111/j.1755-5949.2009.00116.x.
3
肌萎缩侧索硬化症的药物和非药物治疗:一项意大利真实世界数据研究。
Eur J Neurol. 2024 Dec;31(12):e16470. doi: 10.1111/ene.16470. Epub 2024 Sep 19.
4
Comparison of Demographics: National Amyotrophic Lateral Sclerosis Registry and Clinical Trials Data.人口统计学比较:国家肌萎缩侧索硬化症注册库与临床试验数据
J Racial Ethn Health Disparities. 2024 Jul 8. doi: 10.1007/s40615-024-02047-4.
5
Update on recent advances in amyotrophic lateral sclerosis.肌萎缩侧索硬化症的最新进展综述。
J Neurol. 2024 Jul;271(7):4693-4723. doi: 10.1007/s00415-024-12435-9. Epub 2024 May 27.
6
Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective.肌萎缩侧索硬化症的临床试验:系统评价与展望
Brain Commun. 2021 Oct 23;3(4):fcab242. doi: 10.1093/braincomms/fcab242. eCollection 2021.
7
Defining novel functions for cerebrospinal fluid in ALS pathophysiology.定义脑脊液在 ALS 病理生理学中的新功能。
Acta Neuropathol Commun. 2020 Aug 20;8(1):140. doi: 10.1186/s40478-020-01018-0.
Riluzole and amyotrophic lateral sclerosis survival: a population-based study in southern Italy.
利鲁唑与肌萎缩侧索硬化症患者的生存情况:意大利南部的一项基于人群的研究。
Eur J Neurol. 2007 Mar;14(3):262-8. doi: 10.1111/j.1468-1331.2006.01575.x.
4
The ALS/MND prevalence in Sweden estimated by riluzole sales statistics.通过利鲁唑销售统计数据估算的瑞典肌萎缩侧索硬化症/运动神经元病患病率。
Acta Neurol Scand. 2005 Mar;111(3):180-4. doi: 10.1111/j.1600-0404.2005.00384.x.
5
The tolerability of riluzole in the treatment of patients with amyotrophic lateral sclerosis.利鲁唑治疗肌萎缩侧索硬化症患者的耐受性
Expert Opin Drug Saf. 2004 Nov;3(6):525-34. doi: 10.1517/14740338.3.6.525.
6
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group.利鲁唑治疗肌萎缩侧索硬化症的对照试验。肌萎缩侧索硬化症/利鲁唑研究组
N Engl J Med. 1994 Mar 3;330(9):585-91. doi: 10.1056/NEJM199403033300901.